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The longitudinal association between early-life screen-viewing and abdominal adiposity: findings from a multi ethnic birth cohort study

The longitudinal association between early-life screen-viewing and abdominal adiposity: findings from a multi ethnic birth cohort study
The longitudinal association between early-life screen-viewing and abdominal adiposity: findings from a multi ethnic birth cohort study
Importance: screen-viewing in adults has been associated with greater abdominal adiposity, with the magnitude of associations varying by sex and ethnicity, but the evidence is lacking at younger ages. We aimed to investigate sex- and ethnic-specific associations of screen-viewing time at ages 2 and 3 years with abdominal adiposity measured by magnetic resonance imaging at age 4.5 years.

Methods: The Growing Up in Singapore Towards healthy Outcomes is an ongoing prospective mother-offspring cohort study. Parents/caregivers reported the time their child spent viewing television, handheld devices and computer screens at ages 2 and 3 years. Superficial and deep subcutaneous and visceral abdominal adipose tissue volumes were quantified from magnetic resonance images acquired at age 4.5 years. Associations between screen-viewing time and abdominal adipose tissue volumes were examined by multivariable linear regression adjusting for confounding factors.

Results: in the overall sample (n=307), greater total screen-viewing time and handheld device times were associated with higher superficial and deep subcutaneous adipose tissue volumes, but not with visceral adipose tissue volumes. Interactions with child sex were found, with significant associations with superficial and deep subcutaneous and visceral adipose tissue volumes in boys, but not in girls. Among boys, the increases in mean (95% CI) superficial and deep subcutaneous and visceral adipose tissue volumes were 24.3 (9.9, 38.7), 17.6 (7.4, 27.8), and 7.8 (2.1, 13.6) mL per hour increase in daily total screen-viewing time, respectively. Ethnicity-specific analyses showed associations of total screen-viewing time with abdominal adiposity only in Malay children. Television viewing time was not associated with abdominal adiposity.

Conclusion: greater total screen-viewing time (and in particular, handheld device viewing time) was associated with higher abdominal adiposity in boys and Malay children. Additional studies are necessary to confirm these associations and to examine screen-viewing interventions for preventing excessive abdominal adiposity and its adverse cardiometabolic consequences.
0307-0565
1995-2005
Padmapriya, Natarajan
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Tint, Mya Thway
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Sadananthan, Suresh Anand
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Michael, Navin
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Chen, Bozhi
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Cai, Shirong
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Toh, Jia Ying
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Lanca, Carla
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Tan, Kok Hian
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Saw, Seang Mei
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Shek, Lynette
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Chong, Yap-Seng
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Gluckman, Peter D.
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Lee, Yung Seng
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Yap, Fabian
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Fortier, Marielle V.
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Chong, Mary Foong-Fong
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Godfrey, Keith
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Eriksson, Johan G.
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Velan, Sendhil
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Kramer, Michael S.
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Bernard, Jonathan Y.
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Müller-Riemenschneider, Falk
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Padmapriya, Natarajan
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Michael, Navin
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Chen, Bozhi
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Cai, Shirong
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Toh, Jia Ying
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Lanca, Carla
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Tan, Kok Hian
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Saw, Seang Mei
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Shek, Lynette
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Chong, Yap-Seng
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Lee, Yung Seng
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Fortier, Marielle V.
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Chong, Mary Foong-Fong
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Godfrey, Keith
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Eriksson, Johan G.
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Velan, Sendhil
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Kramer, Michael S.
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Bernard, Jonathan Y.
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Müller-Riemenschneider, Falk
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Padmapriya, Natarajan, Tint, Mya Thway, Sadananthan, Suresh Anand, Michael, Navin, Chen, Bozhi, Cai, Shirong, Toh, Jia Ying, Lanca, Carla, Tan, Kok Hian, Saw, Seang Mei, Shek, Lynette, Chong, Yap-Seng, Gluckman, Peter D., Lee, Yung Seng, Yap, Fabian, Fortier, Marielle V., Chong, Mary Foong-Fong, Godfrey, Keith, Eriksson, Johan G., Velan, Sendhil, Kramer, Michael S., Bernard, Jonathan Y. and Müller-Riemenschneider, Falk (2021) The longitudinal association between early-life screen-viewing and abdominal adiposity: findings from a multi ethnic birth cohort study. International Journal of Obesity, 45 (9), 1995-2005. (doi:10.1038/s41366-021-00864-9).

Record type: Article

Abstract

Importance: screen-viewing in adults has been associated with greater abdominal adiposity, with the magnitude of associations varying by sex and ethnicity, but the evidence is lacking at younger ages. We aimed to investigate sex- and ethnic-specific associations of screen-viewing time at ages 2 and 3 years with abdominal adiposity measured by magnetic resonance imaging at age 4.5 years.

Methods: The Growing Up in Singapore Towards healthy Outcomes is an ongoing prospective mother-offspring cohort study. Parents/caregivers reported the time their child spent viewing television, handheld devices and computer screens at ages 2 and 3 years. Superficial and deep subcutaneous and visceral abdominal adipose tissue volumes were quantified from magnetic resonance images acquired at age 4.5 years. Associations between screen-viewing time and abdominal adipose tissue volumes were examined by multivariable linear regression adjusting for confounding factors.

Results: in the overall sample (n=307), greater total screen-viewing time and handheld device times were associated with higher superficial and deep subcutaneous adipose tissue volumes, but not with visceral adipose tissue volumes. Interactions with child sex were found, with significant associations with superficial and deep subcutaneous and visceral adipose tissue volumes in boys, but not in girls. Among boys, the increases in mean (95% CI) superficial and deep subcutaneous and visceral adipose tissue volumes were 24.3 (9.9, 38.7), 17.6 (7.4, 27.8), and 7.8 (2.1, 13.6) mL per hour increase in daily total screen-viewing time, respectively. Ethnicity-specific analyses showed associations of total screen-viewing time with abdominal adiposity only in Malay children. Television viewing time was not associated with abdominal adiposity.

Conclusion: greater total screen-viewing time (and in particular, handheld device viewing time) was associated with higher abdominal adiposity in boys and Malay children. Additional studies are necessary to confirm these associations and to examine screen-viewing interventions for preventing excessive abdominal adiposity and its adverse cardiometabolic consequences.

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Accepted/In Press date: 18 May 2021
e-pub ahead of print date: 9 June 2021
Published date: 9 June 2021
Additional Information: Funding Information: Acknowledgements This research was supported by the Singapore National Research Foundation under its Translational and Clinical Research (TCR) Flagship Programme and administered by the Singapore Ministry of Health’s National Medical Research Council (NMRC), Singapore—NMRC/TCR/004-NUS/2008; NMRC/TCR/ 012-NUHS/2014. Additional funding was provided by the Singapore Institute for Clinical Sciences, Agency for Science Technology and Research (A*STAR), Singapore. KMG was supported by the National Institute for Health Research through the NIHR Southampton Biomedical Research Centre and by the European Union’s Erasmus+ Capacity-Building ENeASEA Project and Seventh Framework Programme (FP7/2007-2013), projects EarlyNutrition and ODIN under grant agreement numbers 289346 and 613977. The authors would like to thank GUSTO study group, operational managers, research fellows, study coordinators, and data management team. The authors greatly appreciate the voluntary participation of all participants and the cooperation of KK Women’s and Children’s Hospital and National University Hospital. The GUSTO study group includes Allan Shep-pard, Amutha Chinnadurai, Anne Eng Neo Goh, Anne Rifkin-Graboi, Anqi Qiu, Arijit Biswas, Bee Wah Lee, Birit F.P. Broekman, Boon Long Quah, Borys Shuter, Chai Kiat Chng, Cheryl Ngo, Choon Looi Bong, Christiani Jeyakumar Henry, Claudia Chi, Cornelia Yin Ing Chee, Yam Thiam Daniel Goh, Doris Fok, E Shyong Tai, Elaine Tham, Elaine Quah Phaik Ling, Evelyn Xiu Ling Loo, George Seow Heong Yeo, Helen Chen, Heng Hao Tan, Hugo P S van Bever, Iliana Magiati, Inez Bik Yun Wong, Ivy Yee-Man Lau, Izzuddin Bin Mohd Aris, Jeevesh Kapur, Jenny L. Richmond, Jerry Kok Yen Chan, Joanna D. Holbrook, Joanne Yoong, Joao N. Ferreira, Jonathan Tze Liang Choo, Joshua J. Gooley, Krishnamoorthy Niduvaje, Kuan Jin Lee, Leher Singh, Lieng Hsi Ling, Lin Lin Su, Ling-Wei Chen, Lourdes Mary Daniel, Marielle V. Fortier, Mark Hanson, Mary Foong-Fong Chong, Mary Rauff, Mei Chien Chua, Melvin Khee-Shing Leow, Michael Meaney, Mya Thway Tint, Neerja Karnani, Ngee Lek, Oon Hoe Teoh, P. C. Wong, Paulin Tay Straughan, Pratibha Agarwal, Queenie Ling Jun Li, Rob M. van Dam, Salome A. Rebello, S. Sendhil Velan, Seng Bin Ang, Shang Chee Chong, Sharon Ng, Shiao-Yng Chan, Shu-E Soh, Sok Bee Lim, Stella Tsotsi, Chin-Ying Stephen Hsu, Sue Anne Toh, Swee Chye Quek, Victor Samuel Rajadurai, Walter Stunkel, Wayne Cutfield, Wee Meng Han, Wei Wei Pang, Yin Bun Cheung, and Yiong Huak Chan. Funding Information: Conflict of interest KMG and YSC report receiving reimbursement for speaking at conferences sponsored by companies selling nutritional products and report being part of an academic consortium that has received research funding from Abbott Nutrition, Nestle, and Danone. No other disclosures were reported. The authors wish to confirm that there has been no significant financial support for this work that could have influenced its outcome. Publisher Copyright: © 2021, The Author(s), under exclusive licence to Springer Nature Limited.

Identifiers

Local EPrints ID: 449416
URI: http://eprints.soton.ac.uk/id/eprint/449416
ISSN: 0307-0565
PURE UUID: e1d56460-59e8-407d-83ad-accd29ea918d
ORCID for Keith Godfrey: ORCID iD orcid.org/0000-0002-4643-0618

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Date deposited: 27 May 2021 16:32
Last modified: 17 Mar 2024 06:35

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Contributors

Author: Natarajan Padmapriya
Author: Mya Thway Tint
Author: Suresh Anand Sadananthan
Author: Navin Michael
Author: Bozhi Chen
Author: Shirong Cai
Author: Jia Ying Toh
Author: Carla Lanca
Author: Kok Hian Tan
Author: Seang Mei Saw
Author: Lynette Shek
Author: Yap-Seng Chong
Author: Peter D. Gluckman
Author: Yung Seng Lee
Author: Fabian Yap
Author: Marielle V. Fortier
Author: Mary Foong-Fong Chong
Author: Keith Godfrey ORCID iD
Author: Johan G. Eriksson
Author: Sendhil Velan
Author: Michael S. Kramer
Author: Jonathan Y. Bernard
Author: Falk Müller-Riemenschneider

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