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The importance of heterogeneity in tumor pathology.

The importance of heterogeneity in tumor pathology.
The importance of heterogeneity in tumor pathology.
Heterogeneity of cell, tissue, and tumor genotype, form, and function confounds clinicopathologic research and therapeutic strategies. Its significance and importance usually are underestimated and underreported, and there is no consistent statistical or biomathematical framework for its interpretation. New technologies for the quantitative study of pathology specimens and a growing awareness of the clinical importance of biodiversity within individual tumors and populations of tumors herald new approaches to the problems posed by dynamic structural and functional complexity in human tumors.
1072-4109
156-163
Rew, D. A.
36dcc3ad-2379-4b61-a468-5c623d796887
Rew, D. A.
36dcc3ad-2379-4b61-a468-5c623d796887

Rew, D. A. (1998) The importance of heterogeneity in tumor pathology. Advances in Anatomic Pathology, 5 (3), 156-163. (doi:10.1097/00125480-199805000-00002).

Record type: Review

Abstract

Heterogeneity of cell, tissue, and tumor genotype, form, and function confounds clinicopathologic research and therapeutic strategies. Its significance and importance usually are underestimated and underreported, and there is no consistent statistical or biomathematical framework for its interpretation. New technologies for the quantitative study of pathology specimens and a growing awareness of the clinical importance of biodiversity within individual tumors and populations of tumors herald new approaches to the problems posed by dynamic structural and functional complexity in human tumors.

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More information

Published date: May 1998
Additional Information: Copyright: This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Identifiers

Local EPrints ID: 449500
URI: http://eprints.soton.ac.uk/id/eprint/449500
ISSN: 1072-4109
PURE UUID: b920676c-ab2b-45ce-b73e-bdbd44df7814
ORCID for D. A. Rew: ORCID iD orcid.org/0000-0002-4518-2667

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Date deposited: 04 Jun 2021 16:30
Last modified: 17 Mar 2024 03:56

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