A pas de deux of osteoporosis and sarcopenia: osteosarcopenia
A pas de deux of osteoporosis and sarcopenia: osteosarcopenia
The musculoskeletal conditions osteoporosis and sarcopenia are highly prevalent in older adults. Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone, whereas sarcopenia is identified by the loss of muscle strength, function and mass. Osteoporosis represents a major health problem contributing to millions of fractures worldwide on an annual basis, whereas sarcopenia is associated with a range of adverse physical and metabolic outcomes. They both affect physical and social function, confidence and quality of life as well as contributing to high health-care costs worldwide. Osteosarcopenia is the term given when both conditions occur concomitantly and it has been suggested that interactions between these two conditions may accelerate individual disease progression as co-existence of osteoporosis and sarcopenia is associated with higher morbidity from falls, fracture, disability as well as mortality. In this review, we will outline the epidemiology, pathogenesis and clinical consequences of osteosarcopenia and discuss available management strategies.
Osteoporosis, epidemiology, management, osteosarcopenia, postmenopausal women, sarcopenia
Laskou, Faidra
3959d6e2-ccfa-4d97-8311-16f27b893365
Patel, Harnish
e1c0826f-d14e-49f3-8049-5b945d185523
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
26 July 2021
Laskou, Faidra
3959d6e2-ccfa-4d97-8311-16f27b893365
Patel, Harnish
e1c0826f-d14e-49f3-8049-5b945d185523
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Laskou, Faidra, Patel, Harnish, Cooper, Cyrus and Dennison, Elaine
(2021)
A pas de deux of osteoporosis and sarcopenia: osteosarcopenia.
Climacteric.
(doi:10.1080/13697137.2021.1951204).
Abstract
The musculoskeletal conditions osteoporosis and sarcopenia are highly prevalent in older adults. Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone, whereas sarcopenia is identified by the loss of muscle strength, function and mass. Osteoporosis represents a major health problem contributing to millions of fractures worldwide on an annual basis, whereas sarcopenia is associated with a range of adverse physical and metabolic outcomes. They both affect physical and social function, confidence and quality of life as well as contributing to high health-care costs worldwide. Osteosarcopenia is the term given when both conditions occur concomitantly and it has been suggested that interactions between these two conditions may accelerate individual disease progression as co-existence of osteoporosis and sarcopenia is associated with higher morbidity from falls, fracture, disability as well as mortality. In this review, we will outline the epidemiology, pathogenesis and clinical consequences of osteosarcopenia and discuss available management strategies.
Text
A pas de deux of osteoporosis and sarcopenia osteosarcopenia
- Version of Record
More information
Accepted/In Press date: 24 June 2021
e-pub ahead of print date: 26 July 2021
Published date: 26 July 2021
Keywords:
Osteoporosis, epidemiology, management, osteosarcopenia, postmenopausal women, sarcopenia
Identifiers
Local EPrints ID: 450549
URI: http://eprints.soton.ac.uk/id/eprint/450549
ISSN: 1369-7137
PURE UUID: 954c8783-03df-4e86-9d1f-14882d2ec223
Catalogue record
Date deposited: 03 Aug 2021 16:31
Last modified: 18 Mar 2024 03:06
Export record
Altmetrics
Contributors
Author:
Faidra Laskou
Author:
Harnish Patel
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics