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A pas de deux of osteoporosis and sarcopenia: osteosarcopenia

A pas de deux of osteoporosis and sarcopenia: osteosarcopenia
A pas de deux of osteoporosis and sarcopenia: osteosarcopenia
The musculoskeletal conditions osteoporosis and sarcopenia are highly prevalent in older adults. Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone, whereas sarcopenia is identified by the loss of muscle strength, function and mass. Osteoporosis represents a major health problem contributing to millions of fractures worldwide on an annual basis, whereas sarcopenia is associated with a range of adverse physical and metabolic outcomes. They both affect physical and social function, confidence and quality of life as well as contributing to high health-care costs worldwide. Osteosarcopenia is the term given when both conditions occur concomitantly and it has been suggested that interactions between these two conditions may accelerate individual disease progression as co-existence of osteoporosis and sarcopenia is associated with higher morbidity from falls, fracture, disability as well as mortality. In this review, we will outline the epidemiology, pathogenesis and clinical consequences of osteosarcopenia and discuss available management strategies.
Osteoporosis, epidemiology, management, osteosarcopenia, postmenopausal women, sarcopenia
1369-7137
Laskou, Faidra
3959d6e2-ccfa-4d97-8311-16f27b893365
Patel, Harnish
e1c0826f-d14e-49f3-8049-5b945d185523
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Laskou, Faidra
3959d6e2-ccfa-4d97-8311-16f27b893365
Patel, Harnish
e1c0826f-d14e-49f3-8049-5b945d185523
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1

Laskou, Faidra, Patel, Harnish, Cooper, Cyrus and Dennison, Elaine (2021) A pas de deux of osteoporosis and sarcopenia: osteosarcopenia. Climacteric. (doi:10.1080/13697137.2021.1951204).

Record type: Review

Abstract

The musculoskeletal conditions osteoporosis and sarcopenia are highly prevalent in older adults. Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone, whereas sarcopenia is identified by the loss of muscle strength, function and mass. Osteoporosis represents a major health problem contributing to millions of fractures worldwide on an annual basis, whereas sarcopenia is associated with a range of adverse physical and metabolic outcomes. They both affect physical and social function, confidence and quality of life as well as contributing to high health-care costs worldwide. Osteosarcopenia is the term given when both conditions occur concomitantly and it has been suggested that interactions between these two conditions may accelerate individual disease progression as co-existence of osteoporosis and sarcopenia is associated with higher morbidity from falls, fracture, disability as well as mortality. In this review, we will outline the epidemiology, pathogenesis and clinical consequences of osteosarcopenia and discuss available management strategies.

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A pas de deux of osteoporosis and sarcopenia osteosarcopenia - Version of Record
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Accepted/In Press date: 24 June 2021
e-pub ahead of print date: 26 July 2021
Published date: 26 July 2021
Keywords: Osteoporosis, epidemiology, management, osteosarcopenia, postmenopausal women, sarcopenia

Identifiers

Local EPrints ID: 450549
URI: http://eprints.soton.ac.uk/id/eprint/450549
ISSN: 1369-7137
PURE UUID: 954c8783-03df-4e86-9d1f-14882d2ec223
ORCID for Faidra Laskou: ORCID iD orcid.org/0000-0002-8481-6343
ORCID for Harnish Patel: ORCID iD orcid.org/0000-0002-0081-1802
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709
ORCID for Elaine Dennison: ORCID iD orcid.org/0000-0002-3048-4961

Catalogue record

Date deposited: 03 Aug 2021 16:31
Last modified: 26 Nov 2021 03:23

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Contributors

Author: Faidra Laskou ORCID iD
Author: Harnish Patel ORCID iD
Author: Cyrus Cooper ORCID iD
Author: Elaine Dennison ORCID iD

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