Antenatal counselling for families whose fetus has neurological anomalies: Part two –risks of adverse outcome in common abnormalities

Abstract

Following diagnosis of a fetal neurological abnormality, prospective parents want to know the best and worst-case scenarios and an estimation of the risk for their fetus having atypical developmental outcome. The literature on developmental outcomes for fetal neurological abnormalities is poor: studies are characterised by retrospective design, small sample size, often no standardised assessment of development, and differing definitions of abnormality. This paper provides an aide-memoir on the risks of adverse neurodevelopmental outcome for ventriculomegaly, cortical abnormalities, microcephaly, macrocephaly, agenesis of the corpus callosum, posterior fossa abnormalities, and myelomeningocele to assist health care professionals in counselling. The data in this paper should be used alongside recommendations on counselling and service design in paper one to provide antenatal counselling.

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ORCID for Brigitte Vollmer: orcid.org/0000-0003-4088-5336

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