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Antenatal counselling for families whose fetus has neurological anomalies: Part two –risks of adverse outcome in common abnormalities

Antenatal counselling for families whose fetus has neurological anomalies: Part two –risks of adverse outcome in common abnormalities
Antenatal counselling for families whose fetus has neurological anomalies: Part two –risks of adverse outcome in common abnormalities
Following diagnosis of a fetal neurological abnormality, prospective parents want to know the best and worst-case scenarios and an estimation of the risk for their fetus having atypical developmental outcome. The literature on developmental outcomes for fetal neurological abnormalities is poor: studies are characterised by retrospective design, small sample size, often no standardised assessment of development, and differing definitions of abnormality. This paper provides an aide-memoir on the risks of adverse neurodevelopmental outcome for ventriculomegaly, cortical abnormalities, microcephaly, macrocephaly, agenesis of the corpus callosum, posterior fossa abnormalities, and myelomeningocele to assist health care professionals in counselling. The data in this paper should be used alongside recommendations on counselling and service design in paper one to provide antenatal counselling.
0012-1622
Hart, Anthony
56db1e01-fa34-4971-b55d-cf09c101c17b
Vasudevan, Chakra
fe07d9e5-ad86-41c1-ac50-8902ac4d316b
Griffiths, Paul
964f37c3-b205-4405-94ce-d736ef817d9b
Foulds, Nicola
cac95d17-52b4-470d-b201-4bb2f7587ee8
Piercy, Hilary
366c39be-d843-41c7-a93a-3a6aca840221
de Lacy, Patricia
c0cc98f4-3a0d-43ca-b13d-3bc218a6cf35
Boxall, Sally
225f990f-6ec9-434c-b5f7-9e59e7c0c717
Howe, David
3a4ff013-9aac-4e5f-bb15-67df52fc97fa
Vollmer, Brigitte
044f8b55-ba36-4fb2-8e7e-756ab77653ba
Hart, Anthony
56db1e01-fa34-4971-b55d-cf09c101c17b
Vasudevan, Chakra
fe07d9e5-ad86-41c1-ac50-8902ac4d316b
Griffiths, Paul
964f37c3-b205-4405-94ce-d736ef817d9b
Foulds, Nicola
cac95d17-52b4-470d-b201-4bb2f7587ee8
Piercy, Hilary
366c39be-d843-41c7-a93a-3a6aca840221
de Lacy, Patricia
c0cc98f4-3a0d-43ca-b13d-3bc218a6cf35
Boxall, Sally
225f990f-6ec9-434c-b5f7-9e59e7c0c717
Howe, David
3a4ff013-9aac-4e5f-bb15-67df52fc97fa
Vollmer, Brigitte
044f8b55-ba36-4fb2-8e7e-756ab77653ba

Hart, Anthony, Vasudevan, Chakra, Griffiths, Paul, Foulds, Nicola, Piercy, Hilary, de Lacy, Patricia, Boxall, Sally, Howe, David and Vollmer, Brigitte (2021) Antenatal counselling for families whose fetus has neurological anomalies: Part two –risks of adverse outcome in common abnormalities. Developmental Medicine & Child Neurology. (In Press)

Record type: Review

Abstract

Following diagnosis of a fetal neurological abnormality, prospective parents want to know the best and worst-case scenarios and an estimation of the risk for their fetus having atypical developmental outcome. The literature on developmental outcomes for fetal neurological abnormalities is poor: studies are characterised by retrospective design, small sample size, often no standardised assessment of development, and differing definitions of abnormality. This paper provides an aide-memoir on the risks of adverse neurodevelopmental outcome for ventriculomegaly, cortical abnormalities, microcephaly, macrocephaly, agenesis of the corpus callosum, posterior fossa abnormalities, and myelomeningocele to assist health care professionals in counselling. The data in this paper should be used alongside recommendations on counselling and service design in paper one to provide antenatal counselling.

Text
Fetal counselling review part 2 - R4 No tracks - Accepted Manuscript
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More information

Accepted/In Press date: 12 August 2021

Identifiers

Local EPrints ID: 450951
URI: http://eprints.soton.ac.uk/id/eprint/450951
ISSN: 0012-1622
PURE UUID: c821b68f-63d8-4674-be1b-b4e85a685efb
ORCID for Brigitte Vollmer: ORCID iD orcid.org/0000-0003-4088-5336

Catalogue record

Date deposited: 25 Aug 2021 16:32
Last modified: 26 Aug 2021 01:42

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Contributors

Author: Anthony Hart
Author: Chakra Vasudevan
Author: Paul Griffiths
Author: Nicola Foulds
Author: Hilary Piercy
Author: Patricia de Lacy
Author: Sally Boxall
Author: David Howe

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