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Powered respirators are effective, sustainable, and cost-effective personal protective equipment for SARS-CoV-2

Powered respirators are effective, sustainable, and cost-effective personal protective equipment for SARS-CoV-2
Powered respirators are effective, sustainable, and cost-effective personal protective equipment for SARS-CoV-2
Objectives: The provision of high-quality personal protective equipment (PPE) has been a critical challenge during the COVID-19 pandemic. We evaluated an alternative strategy, mass deployment of a powered air-purifying respirator (PeRSo), in a large university hospital.

Methods: We performed prospective user feedback via questionnaires sent to healthcare workers (HCWs) issued PeRSos, economic analysis, and evaluated the real-world impact.

Results: Where paired responses were available, PeRSo was preferred over droplet precautions for comfort, patient response, overall experience, and subjective feeling of safety. For all responses, more participants reported the overall experience being rated “Very good” more frequently for PeRSo. The primary limitation identified was impairment of hearing. Economic simulation exercises revealed that the adoption of PeRSo within ICU is associated with net cost savings in the majority of scenarios and savings increased progressively with greater ITU occupancy. In evaluation during the second UK wave, over 3,600 respirators were deployed, all requested by staff, which were associated with a low staff absence relative to most comparator hospitals.

Conclusions: Health services should consider a widespread implementation of powered reusable respirators as a safe and sustainable solution for the protection of HCWs as SARS-CoV-2 becomes an endemic viral illness.
2673-3129
1-13
Munro, Alasdair
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Prieto, Jacqui
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Mentzakis, Emmanouil
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Mansour, Mohammed AM
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Mahobia, Nitin
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Baker, Peter
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Herbert, Sarah
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Smith, Trevor
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Hine, Matthew
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Hall, Joann
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McClarren, Angie
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Davidson, Mike
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Brooks, Julie
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Fisher, Jane
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Griffiths, David
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Morgan, Hywel
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Giulietti, Corrado
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Faust, Saul
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Elkington, Paul
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Munro, Alasdair
59dacf7d-5977-49c4-b562-b2c719c9dcf4
Prieto, Jacqui
47dd42cd-35d5-4ece-8fc6-fdb8fe1f01cc
Mentzakis, Emmanouil
c0922185-18c7-49c2-a659-8ee6d89b5d74
Mansour, Mohammed AM
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Mahobia, Nitin
f51120ec-4afa-4483-a229-68dd38b73c29
Baker, Peter
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Herbert, Sarah
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Smith, Trevor
53e6838c-2e95-4c8f-9325-53163ab6255d
Hine, Matthew
6359ae22-87b6-4d4f-9b04-0cbd201195ff
Hall, Joann
4036912e-4d9a-4104-b70c-445867beeddc
McClarren, Angie
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Davidson, Mike
9675980e-44f1-4a6a-97e0-98d90aade9b2
Brooks, Julie
a0695c66-5295-492b-8846-1e81402824a4
Fisher, Jane
84a276dc-c510-447a-ad93-eb07f7ccae5b
Griffiths, David
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Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Giulietti, Corrado
c662221c-fad3-4456-bfe3-78f8a5211158
Faust, Saul
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Elkington, Paul
60828c7c-3d32-47c9-9fcc-6c4c54c35a15

Munro, Alasdair, Prieto, Jacqui, Mentzakis, Emmanouil, Mansour, Mohammed AM, Mahobia, Nitin, Baker, Peter, Herbert, Sarah, Smith, Trevor, Hine, Matthew, Hall, Joann, McClarren, Angie, Davidson, Mike, Brooks, Julie, Fisher, Jane, Griffiths, David, Morgan, Hywel, Giulietti, Corrado, Faust, Saul and Elkington, Paul (2021) Powered respirators are effective, sustainable, and cost-effective personal protective equipment for SARS-CoV-2. Frontiers in Medical Technology, 3 (October 2021), 1-13, [729658]. (doi:10.3389/fmedt.2021.729658).

Record type: Article

Abstract

Objectives: The provision of high-quality personal protective equipment (PPE) has been a critical challenge during the COVID-19 pandemic. We evaluated an alternative strategy, mass deployment of a powered air-purifying respirator (PeRSo), in a large university hospital.

Methods: We performed prospective user feedback via questionnaires sent to healthcare workers (HCWs) issued PeRSos, economic analysis, and evaluated the real-world impact.

Results: Where paired responses were available, PeRSo was preferred over droplet precautions for comfort, patient response, overall experience, and subjective feeling of safety. For all responses, more participants reported the overall experience being rated “Very good” more frequently for PeRSo. The primary limitation identified was impairment of hearing. Economic simulation exercises revealed that the adoption of PeRSo within ICU is associated with net cost savings in the majority of scenarios and savings increased progressively with greater ITU occupancy. In evaluation during the second UK wave, over 3,600 respirators were deployed, all requested by staff, which were associated with a low staff absence relative to most comparator hospitals.

Conclusions: Health services should consider a widespread implementation of powered reusable respirators as a safe and sustainable solution for the protection of HCWs as SARS-CoV-2 becomes an endemic viral illness.

Text
210907 PeRSo Frontiers Clean - Accepted Manuscript
Available under License Creative Commons Attribution.
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More information

Accepted/In Press date: 7 September 2021
Published date: 14 October 2021
Additional Information: This study was supported by staff employed by the NIHR Southampton Clinical Research Facility (AM and SF). SF was an NIHR Senior Investigator. PE was supported by MR/P023754/1. The funders had no input into the study design or analysis.

Identifiers

Local EPrints ID: 451510
URI: http://eprints.soton.ac.uk/id/eprint/451510
ISSN: 2673-3129
PURE UUID: 0117d726-a599-42e5-8a88-5618372e4f59
ORCID for Jacqui Prieto: ORCID iD orcid.org/0000-0002-5524-6775
ORCID for Emmanouil Mentzakis: ORCID iD orcid.org/0000-0003-1761-209X
ORCID for Hywel Morgan: ORCID iD orcid.org/0000-0003-4850-5676
ORCID for Corrado Giulietti: ORCID iD orcid.org/0000-0003-2986-4438
ORCID for Saul Faust: ORCID iD orcid.org/0000-0003-3410-7642
ORCID for Paul Elkington: ORCID iD orcid.org/0000-0003-0390-0613

Catalogue record

Date deposited: 05 Oct 2021 16:30
Last modified: 17 Mar 2024 03:29

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Contributors

Author: Alasdair Munro
Author: Jacqui Prieto ORCID iD
Author: Mohammed AM Mansour
Author: Nitin Mahobia
Author: Peter Baker
Author: Sarah Herbert
Author: Trevor Smith
Author: Matthew Hine
Author: Joann Hall
Author: Angie McClarren
Author: Mike Davidson
Author: Julie Brooks
Author: Jane Fisher
Author: David Griffiths
Author: Hywel Morgan ORCID iD
Author: Saul Faust ORCID iD
Author: Paul Elkington ORCID iD

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