READ ME File For 'Dataset title'

Dataset DOI: 10.5258/SOTON/D2018

Date that the file was created: 27th October 2021

-------------------
GENERAL INFORMATION
-------------------

ReadMe Author: Matthew Quansah, University of Southampton

Date of data collection: 2020/09/02 - 2020/10/21

Information about geographic location of data collection: Southampton General Hospital

Related projects:
ADD IN

--------------------------
SHARING/ACCESS INFORMATION
-------------------------- 

Licenses/restrictions placed on the data, or limitations of reuse: CC-NY-NC-SA 4.0

Recommended citation for the data:

Quanash, M., Hickinbottom, K, Denton, S., Gavin, J., Fulmali, A., Dawson, S., Alderton, M., Williams, S., Afzal, N. A., Grimshaw, K. & Lajeunesse, M. (2021) 'Persistent gut symptoms in infants with non-IgE cow’s milk allergy: dataset', University of Southampton, DOI: 10.5258/SOTON/D2018



This dataset supports the publication:
AUTHORS: Matthew Quansah, Katie Hickinbottom, Sally-Ann Denton, Joan Gavin, Amruta Fulmali, Sara Dawson, Mark Alderton, Sarah Williams, Nadeem Afzal, Kate Grimshaw, Mich Erlewyn-Lajeunesse
TITLE: Persistent gut symptoms in infants with non-IgE cow’s milk allergy
JOURNAL: International Archives of Allergy and Immunology
PAPER DOI IF KNOWN: to be confirmed


--------------------
DATA & FILE OVERVIEW
--------------------

This dataset contains:

This dataset contains: An anonymous list of infants diagnosed with non-IgE cow’s milk allergy with their diets, symptoms, and anthropometric data all documented at follow-up hospital visits, over 18 months.
Relationship between files, if important for context:  


--------------------------
METHODOLOGICAL INFORMATION
--------------------------

Data was entered into a pre-formed data collection sheet, in Excel.

Excel spreadsheet of data set was coded and then analysed in IBM SPSS version 27.

Environmental conditions: Infants seen in clinic.

Original patient information was stored on NHS systems in a password protected file. Infant information was assigned a unique identifier code to anonymise infants. 

Matthew Quansah (MQ) did the study under the supervision of MEL, JG, and Kate Grimshaw. He was assisted by Amruta Fulmali. A preliminary study performed by Katie Hickinbottom formed the basis of this study. Sara Dawson, S-A Denton, Mark Alderton, Sarah Williams, Nadeem Afzal provided patients of the study, were involved in the design of the project and review of the data analysis. MQ and MEL wrote the paper, and all authors were involved in the preparation of the final report

--------------------------
DATA-SPECIFIC INFORMATION 
--------------------------

Number of variables: 45 Variables (N.B. Laxative PN / Lax PN listed in “yes or no” and an option for quantification) 

Number of cases/rows: 157 Infants

Variable list, defining any abbreviations, units of measure, codes or symbols used:

•	Age at referral (weeks)
•	Age at 1st appt (wks)
•	Appt Wait Time (Weeks)
•	Age 1st FUP (wks)
•	Age at 9m FUP (mo)
•	Age at 18mo FUP (mo)
•	Age at discharge in weeks

•	Sex
•	Method of delivery
•	Neonatal antibiotics
•	Age when symptoms first started
•	Age exclusion diet started (months)
•	Route of referral


At presentation (PN)
•	Weigh(kg) PN
•	Z-score weight PN
•	Lengt(cm) PN
•	Z-score Length PN
•	Breast fed PN
•	Maternal exclusion diet PN
•	Excludes: Soy, wheat, other? PN

•	Formula PN
•	Eating solid foods? PN
•	Stage Milk ladder PN
•	Feed PN
•	ResEpi PN

•	Hard stools PN
•	Loose stools PN
•	Alternating stools PN
•	Stool freq (per day) PN
•	Infant colic PN
•	Back arching PN

•	Unsettled PN
•	Irritable PN
•	Reflux / Vom PN
•	Bloody stools PN
•	Eczema PN
•	Cough / wheeze PN

•	Laxative PN
•	Lax PN
•	Anti-reflux Type PN
•	Anti-reflux PN
•	Promotility Type PN
•	Promotility PN
•	Probiotic PN
•	Discharge [date]


FUP – “Follow-up”
Appt – “Appointment”
PN – “Presentation [to us]”
PGS – “Persistent gut symptoms”
Lax – “Laxative”
Anti-reflux – “Anti reflux medication”
AAF – “Amino acid formula”
EHF – “Extensively hydrolysed formula”
ResEpi – “Residual cow’s milk protein”
Weigh – “Weight (kg)”
Lengt – “Length (cm)”
@ - “at”
2M – “2 months follow-up”
4M – “4 months follow-up”
6M - “6 months follow-up”
12M - “12 months follow-up”
18M - “18 months follow-up”
   
Missing data codes: No codes have been used to represent missing data.

Specialized formats or other abbreviations used: 
GP – “General practitioner”
A&E – “Accident and emergency”
HV – “Health visitor”
Stool freq – “Stool frequency”