RSV: perspectives to strengthen the need for protection in all infants
RSV: perspectives to strengthen the need for protection in all infants
Respiratory syncytial virus (RSV)-the most common viral cause of bronchiolitis-is a significant cause of serious illness among young children between the ages of 0-5 years and is especially concerning in the first year of life. Globally, RSV is a common cause of childhood acute lower respiratory illness (ALRI) and a major cause of hospital admissions in young children and infants and represents a substantial burden for health-care systems. This burden is strongly felt as there are currently no effective preventative options that are available for all infants. However, a renaissance in RSV prevention strategies is unfolding, with several new prophylactic options such as monoclonal antibodies and maternal vaccinations that are soon to be available. A key concern is that health decision makers and systems may not be ready to take full advantage of forthcoming technological innovations. A multi-stakeholder approach is necessary to bridge data gaps to fully utilise upcoming options. Knowledge must be made available at multiple levels to ensure that parents and doctors are aware of preventative options, but also to ensure that stakeholders and policymakers are given the necessary information to best advise implementation strategies.
Global childhood disease burden, Infant and child health, Infant mortality, RSV, Respiratory syncytial virus, RSV-ALRI, RSV-associated acute lower respiratory illness, Vaccine
Navarro Alonso, Jose Antonio
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Bont, Louis J
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Bozzola, Elena
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Herting, Egbert
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Lega, Federico
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Mader, Silke
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Nunes, Marta C
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Ramilo, Octavio
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Valiotis, George
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Olivier, Catherine Weil
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Yates, Ann
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Faust, Saul N
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21 October 2021
Navarro Alonso, Jose Antonio
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Bont, Louis J
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Bozzola, Elena
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Herting, Egbert
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Lega, Federico
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Mader, Silke
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Nunes, Marta C
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Ramilo, Octavio
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Valiotis, George
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Olivier, Catherine Weil
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Yates, Ann
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Faust, Saul N
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Navarro Alonso, Jose Antonio, Bont, Louis J, Bozzola, Elena, Herting, Egbert, Lega, Federico, Mader, Silke, Nunes, Marta C, Ramilo, Octavio, Valiotis, George, Olivier, Catherine Weil, Yates, Ann and Faust, Saul N
(2021)
RSV: perspectives to strengthen the need for protection in all infants.
Emerging Themes in Epidemiology, 18 (1), [15].
(doi:10.1186/s12982-021-00104-5).
Abstract
Respiratory syncytial virus (RSV)-the most common viral cause of bronchiolitis-is a significant cause of serious illness among young children between the ages of 0-5 years and is especially concerning in the first year of life. Globally, RSV is a common cause of childhood acute lower respiratory illness (ALRI) and a major cause of hospital admissions in young children and infants and represents a substantial burden for health-care systems. This burden is strongly felt as there are currently no effective preventative options that are available for all infants. However, a renaissance in RSV prevention strategies is unfolding, with several new prophylactic options such as monoclonal antibodies and maternal vaccinations that are soon to be available. A key concern is that health decision makers and systems may not be ready to take full advantage of forthcoming technological innovations. A multi-stakeholder approach is necessary to bridge data gaps to fully utilise upcoming options. Knowledge must be made available at multiple levels to ensure that parents and doctors are aware of preventative options, but also to ensure that stakeholders and policymakers are given the necessary information to best advise implementation strategies.
Text
s12982-021-00104-5
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Accepted/In Press date: 11 October 2021
Published date: 21 October 2021
Additional Information:
Funding Information:
The authors thank Martin Friede, Coordinator of the Initiative for Vaccine Research (IVR) at the World Health Organization in Geneva, for his participation as an observer. The authors acknowledge Subhadra Menon, Global Health writer, for providing editorial assistance with the preparation of this manuscript, funded by Sanofi Pasteur and AstraZeneca.
Funding Information:
The authors thank Martin Friede, Coordinator of the Initiative for Vaccine Research (IVR) at the World Health Organization in Geneva, for his participation as an observer. The authors acknowledge Subhadra Menon, Global Health writer, for providing editorial assistance with the preparation of this manuscript, funded by Sanofi Pasteur and AstraZeneca.
Publisher Copyright:
© 2021, The Author(s).
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
Keywords:
Global childhood disease burden, Infant and child health, Infant mortality, RSV, Respiratory syncytial virus, RSV-ALRI, RSV-associated acute lower respiratory illness, Vaccine
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Local EPrints ID: 453552
URI: http://eprints.soton.ac.uk/id/eprint/453552
ISSN: 1742-7622
PURE UUID: f676fa8b-8993-4ed1-9be9-3a4427dfa05f
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Date deposited: 19 Jan 2022 17:45
Last modified: 17 Mar 2024 03:06
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Contributors
Author:
Jose Antonio Navarro Alonso
Author:
Louis J Bont
Author:
Elena Bozzola
Author:
Egbert Herting
Author:
Federico Lega
Author:
Silke Mader
Author:
Marta C Nunes
Author:
Octavio Ramilo
Author:
George Valiotis
Author:
Catherine Weil Olivier
Author:
Ann Yates
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