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Conformational control of HCl co-transporter: imidazole functionalised isophthalamide vs. 2,6-dicarboxamidopyridine

Conformational control of HCl co-transporter: imidazole functionalised isophthalamide vs. 2,6-dicarboxamidopyridine
Conformational control of HCl co-transporter: imidazole functionalised isophthalamide vs. 2,6-dicarboxamidopyridine
Replacement of the central isophthalamide core in a synthetic HCl receptor, with a 2,6-dicarboxamidopyridine, leads to a more preorganized molecular structure that exhibits higher chloride affinity and membrane transport flux.
hci co-transport, supramolecular chemistry, anion complexation
1359-7345
1736-1738
Gale, Philip A.
c840b7e9-6847-4843-91af-fa0f8563d943
Garric, Joachim
8683435f-46de-4a6a-ab1c-784a563bd30e
Light, Mark E.
cf57314e-6856-491b-a8d2-2dffc452e161
McNally, Beth A.
77a76472-491b-4239-a0ad-59999893988a
Smith, Bradley D.
fd0bfcd3-c3e7-46ac-a225-60abc125d4e8
Gale, Philip A.
c840b7e9-6847-4843-91af-fa0f8563d943
Garric, Joachim
8683435f-46de-4a6a-ab1c-784a563bd30e
Light, Mark E.
cf57314e-6856-491b-a8d2-2dffc452e161
McNally, Beth A.
77a76472-491b-4239-a0ad-59999893988a
Smith, Bradley D.
fd0bfcd3-c3e7-46ac-a225-60abc125d4e8

Gale, Philip A., Garric, Joachim, Light, Mark E., McNally, Beth A. and Smith, Bradley D. (2007) Conformational control of HCl co-transporter: imidazole functionalised isophthalamide vs. 2,6-dicarboxamidopyridine. Chemical Communications, 2007 (17), 1736-1738. (doi:10.1039/b703259E).

Record type: Article

Abstract

Replacement of the central isophthalamide core in a synthetic HCl receptor, with a 2,6-dicarboxamidopyridine, leads to a more preorganized molecular structure that exhibits higher chloride affinity and membrane transport flux.

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Published date: 2007
Keywords: hci co-transport, supramolecular chemistry, anion complexation
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Identifiers

Local EPrints ID: 45372
URI: http://eprints.soton.ac.uk/id/eprint/45372
DOI: doi:10.1039/b703259E
ISSN: 1359-7345
PURE UUID: 51d5a60f-a012-4eb1-8651-e2a035b5a486
ORCID for Philip A. Gale: ORCID iD orcid.org/0000-0001-9751-4910
ORCID for Mark E. Light: ORCID iD orcid.org/0000-0002-0585-0843

Catalogue record

Date deposited: 02 Apr 2007
Last modified: 16 Mar 2024 03:16

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Contributors

Author: Philip A. Gale ORCID iD
Author: Joachim Garric
Author: Mark E. Light ORCID iD
Author: Beth A. McNally
Author: Bradley D. Smith

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