The University of Southampton
University of Southampton Institutional Repository

Treadmill training for individuals with multiple sclerosis: a pilot randomised trial

Treadmill training for individuals with multiple sclerosis: a pilot randomised trial
Treadmill training for individuals with multiple sclerosis: a pilot randomised trial
This pilot study investigated whether 4 weeks of aerobic treadmill training in individuals with multiple sclerosis (MS) improved mobility and reduced fatigue. Individuals with MS were recruited to this prospective, randomised controlled trial. Individuals were assessed at baseline, week 7 and 12 with a 10 metre timed walk, a 2 minute walk, the Rivermead Mobility Index, and the Fatigue Severity Scale. After a pre-assessment familiarisation session and a baseline assessment, individuals were randomly allocated to an initial intervention or delayed intervention group. Treadmill training consisted of 4 weeks of supervised aerobic exercise delivered weeks 3–6 in the immediate group and 8–11 in the delayed group. Of the initial 19 recruits, 16 individuals completed the study. There was a significant difference in walking endurance between the delayed and immediate groups at baseline (p<0.05). On reassessment in week 7, decreases in 10 metre walk time were found in both groups, which was significant in the immediate group (p<0.05). The 2 minute walk distance significantly increased in both groups (p<0.05). In the training group, reassessed at week 12 after training ceased, there was a return towards baseline scores. No significant changes in fatigue scores were found. This study showed that in individuals with MS, aerobic treadmill training is feasible and well tolerated. Walking speed and endurance increased following training with no increase in reported fatigue. Detraining occurred in the period following training. A larger randomised clinical trial is warranted.
Abbreviations: APMHR, age predicted maximum heart rate; FSS, Fatigue Severity Scale; GNDS, Guy’s Neurological Disability Scale; MS, multiple sclerosis; RMI, Rivermead Mobility Index.
ms, treadmill training, speed, endurance, fatigue
0022-3050
531-533
van den Berg, M.
3a120dad-151d-4e84-8d19-d82fb8a411ef
Dawes, H.
484b4342-f8bd-4f53-9132-d8e674980844
Wade, D.T.
4a5bd5f0-7a92-438e-b548-aaf8cd982315
Newman, M.
18862192-d5f1-4765-913c-61e63e3e3d05
Burridge, J.
0110e9ea-0884-4982-a003-cb6307f38f64
Izadi, H.
5ec0a019-4147-4c9e-9234-42c1ae7939c8
Sackley, C.M.
7559cbc1-5be7-43d4-ba31-5e4e3101dab9
van den Berg, M.
3a120dad-151d-4e84-8d19-d82fb8a411ef
Dawes, H.
484b4342-f8bd-4f53-9132-d8e674980844
Wade, D.T.
4a5bd5f0-7a92-438e-b548-aaf8cd982315
Newman, M.
18862192-d5f1-4765-913c-61e63e3e3d05
Burridge, J.
0110e9ea-0884-4982-a003-cb6307f38f64
Izadi, H.
5ec0a019-4147-4c9e-9234-42c1ae7939c8
Sackley, C.M.
7559cbc1-5be7-43d4-ba31-5e4e3101dab9

van den Berg, M., Dawes, H., Wade, D.T., Newman, M., Burridge, J., Izadi, H. and Sackley, C.M. (2006) Treadmill training for individuals with multiple sclerosis: a pilot randomised trial. Journal of Neurology Neurosurgery and Psychiatry, 77 (4), 531-533. (doi:10.1136/jnnp.2005.064410).

Record type: Article

Abstract

This pilot study investigated whether 4 weeks of aerobic treadmill training in individuals with multiple sclerosis (MS) improved mobility and reduced fatigue. Individuals with MS were recruited to this prospective, randomised controlled trial. Individuals were assessed at baseline, week 7 and 12 with a 10 metre timed walk, a 2 minute walk, the Rivermead Mobility Index, and the Fatigue Severity Scale. After a pre-assessment familiarisation session and a baseline assessment, individuals were randomly allocated to an initial intervention or delayed intervention group. Treadmill training consisted of 4 weeks of supervised aerobic exercise delivered weeks 3–6 in the immediate group and 8–11 in the delayed group. Of the initial 19 recruits, 16 individuals completed the study. There was a significant difference in walking endurance between the delayed and immediate groups at baseline (p<0.05). On reassessment in week 7, decreases in 10 metre walk time were found in both groups, which was significant in the immediate group (p<0.05). The 2 minute walk distance significantly increased in both groups (p<0.05). In the training group, reassessed at week 12 after training ceased, there was a return towards baseline scores. No significant changes in fatigue scores were found. This study showed that in individuals with MS, aerobic treadmill training is feasible and well tolerated. Walking speed and endurance increased following training with no increase in reported fatigue. Detraining occurred in the period following training. A larger randomised clinical trial is warranted.
Abbreviations: APMHR, age predicted maximum heart rate; FSS, Fatigue Severity Scale; GNDS, Guy’s Neurological Disability Scale; MS, multiple sclerosis; RMI, Rivermead Mobility Index.

This record has no associated files available for download.

More information

Published date: 1 April 2006
Additional Information: Short report.
Keywords: ms, treadmill training, speed, endurance, fatigue

Identifiers

Local EPrints ID: 45422
URI: http://eprints.soton.ac.uk/id/eprint/45422
ISSN: 0022-3050
PURE UUID: 32dc31ff-0ac5-44a5-b67f-420f42ada18d
ORCID for J. Burridge: ORCID iD orcid.org/0000-0003-3497-6725

Catalogue record

Date deposited: 28 Mar 2007
Last modified: 16 Mar 2024 02:57

Export record

Altmetrics

Contributors

Author: M. van den Berg
Author: H. Dawes
Author: D.T. Wade
Author: M. Newman
Author: J. Burridge ORCID iD
Author: H. Izadi
Author: C.M. Sackley

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×