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Frailty, multimorbidity and polypharmacy

Frailty, multimorbidity and polypharmacy
Frailty, multimorbidity and polypharmacy

Frailty and multimorbidity are interrelated complex syndromes. Individuals living with frailty are likely to be multimorbid, but not all multimorbid individuals are frail. Frailty and multimorbidity are principal causes of polypharmacy. In combination, they are associated with significant healthcare use, unscheduled hospital admissions and mortality. However, multiple medication use is not always inappropriate. Early detection of frailty, patient-centred decision-making and review of multimorbid conditions underpinned by principles of comprehensive geriatric assessment are the cornerstones of patient management.

Comprehensive geriatric assessment, MRCP, deprescribing, homeostasis, long-term conditions, vulnerability
1357-3039
166-172
Woolford, Stephen J.
f72c05b4-0f71-4a63-a9e8-6d798a57f2db
Aggarwal, Pritti
d13e6516-5b53-4789-b627-115fcebd0d2b
Sheikh, Claire J
eab31d73-d098-4dce-9d0c-3254f3db277c
Patel, Harnish
e1c0826f-d14e-49f3-8049-5b945d185523
Woolford, Stephen J.
f72c05b4-0f71-4a63-a9e8-6d798a57f2db
Aggarwal, Pritti
d13e6516-5b53-4789-b627-115fcebd0d2b
Sheikh, Claire J
eab31d73-d098-4dce-9d0c-3254f3db277c
Patel, Harnish
e1c0826f-d14e-49f3-8049-5b945d185523

Woolford, Stephen J., Aggarwal, Pritti, Sheikh, Claire J and Patel, Harnish (2021) Frailty, multimorbidity and polypharmacy. Medicine, 49 (3), 166-172. (doi:10.1016/j.mpmed.2020.12.010).

Record type: Article

Abstract

Frailty and multimorbidity are interrelated complex syndromes. Individuals living with frailty are likely to be multimorbid, but not all multimorbid individuals are frail. Frailty and multimorbidity are principal causes of polypharmacy. In combination, they are associated with significant healthcare use, unscheduled hospital admissions and mortality. However, multiple medication use is not always inappropriate. Early detection of frailty, patient-centred decision-making and review of multimorbid conditions underpinned by principles of comprehensive geriatric assessment are the cornerstones of patient management.

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More information

e-pub ahead of print date: 22 January 2021
Published date: March 2021
Keywords: Comprehensive geriatric assessment, MRCP, deprescribing, homeostasis, long-term conditions, vulnerability

Identifiers

Local EPrints ID: 454238
URI: http://eprints.soton.ac.uk/id/eprint/454238
ISSN: 1357-3039
PURE UUID: 5bb32ff3-3348-42a5-a66b-fe3616f97690
ORCID for Harnish Patel: ORCID iD orcid.org/0000-0002-0081-1802

Catalogue record

Date deposited: 03 Feb 2022 17:46
Last modified: 28 Apr 2022 01:58

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Contributors

Author: Stephen J. Woolford
Author: Pritti Aggarwal
Author: Claire J Sheikh
Author: Harnish Patel ORCID iD

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