Advances in atopic dermatitis
Advances in atopic dermatitis
Atopic dermatitis (AD) is a common inflammatory skin disease characterised by itch and is responsible for significant reduction in quality of life. While AD primarily arises in those under the age of 2 years, it is frequently persistent into adulthood. Recognition of AD is important for the general physician, especially to distinguish causes of acute flares that may present in any medical setting, such as eczema herpeticum and associated allergic reactions. While, to date, treatments have largely focused on broad spectrum immunomodulation with corticosteroids or systemic therapies (such as ciclosporin and methotrexate), increased knowledge in the pathophysiology of the disease has recently led to the expansion of treatment options available for those suffering with AD, and the new drugs on the horizon promise a previously unimagined potential for effective and safe treatment.
177 - 181
Ardern-Jones, Michael
7ac43c24-94ab-4d19-ba69-afaa546bec90
Plant, Alice
afc8ebf8-5834-4a8c-813e-a825b2b86a8f
1 May 2021
Ardern-Jones, Michael
7ac43c24-94ab-4d19-ba69-afaa546bec90
Plant, Alice
afc8ebf8-5834-4a8c-813e-a825b2b86a8f
Abstract
Atopic dermatitis (AD) is a common inflammatory skin disease characterised by itch and is responsible for significant reduction in quality of life. While AD primarily arises in those under the age of 2 years, it is frequently persistent into adulthood. Recognition of AD is important for the general physician, especially to distinguish causes of acute flares that may present in any medical setting, such as eczema herpeticum and associated allergic reactions. While, to date, treatments have largely focused on broad spectrum immunomodulation with corticosteroids or systemic therapies (such as ciclosporin and methotrexate), increased knowledge in the pathophysiology of the disease has recently led to the expansion of treatment options available for those suffering with AD, and the new drugs on the horizon promise a previously unimagined potential for effective and safe treatment.
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Published date: 1 May 2021
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Local EPrints ID: 454724
URI: http://eprints.soton.ac.uk/id/eprint/454724
ISSN: 1470-2118
PURE UUID: fc5ec31a-7e41-491e-864d-4af53facad9d
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Date deposited: 22 Feb 2022 17:31
Last modified: 17 Mar 2024 03:10
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Author:
Alice Plant
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