Sampson, A. P. (2001) IL-5 priming of eosinophil function in asthma. Clinical and Experimental Allergy, 31 (4), 513-517. (doi:10.1046/j.1365-2222.2001.01046.x).
Abstract
Eosinophils were once thought to help to resolve acute asthma by scavenging allergens and cellular debris in the airway, but their prevalence in the airways and blood of persistent asthmatics and their ability to produce toxic granule proteins, pro-inflammatory cytokines, oxygen radicals and lipid mediators incriminates them as principal culprits of airway inflammation in asthma.
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