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IL-5 priming of eosinophil function in asthma

IL-5 priming of eosinophil function in asthma
IL-5 priming of eosinophil function in asthma
Eosinophils were once thought to help to resolve acute asthma by scavenging allergens and cellular debris in the airway, but their prevalence in the airways and blood of persistent asthmatics and their ability to produce toxic granule proteins, pro-inflammatory cytokines, oxygen radicals and lipid mediators incriminates them as principal culprits of airway inflammation in asthma.
0954-7894
513-517
Sampson, A. P.
4ca76f6f-ff35-425d-a7e7-c2bd2ea2df60
Sampson, A. P.
4ca76f6f-ff35-425d-a7e7-c2bd2ea2df60

Sampson, A. P. (2001) IL-5 priming of eosinophil function in asthma. Clinical and Experimental Allergy, 31 (4), 513-517. (doi:10.1046/j.1365-2222.2001.01046.x).

Record type: Editorial

Abstract

Eosinophils were once thought to help to resolve acute asthma by scavenging allergens and cellular debris in the airway, but their prevalence in the airways and blood of persistent asthmatics and their ability to produce toxic granule proteins, pro-inflammatory cytokines, oxygen radicals and lipid mediators incriminates them as principal culprits of airway inflammation in asthma.

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Published date: 2001

Identifiers

Local EPrints ID: 455372
URI: http://eprints.soton.ac.uk/id/eprint/455372
ISSN: 0954-7894
PURE UUID: 1915395d-bd06-4a7b-89a0-94a963b01cc7
ORCID for A. P. Sampson: ORCID iD orcid.org/0009-0008-9653-8935

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Date deposited: 18 Mar 2022 17:59
Last modified: 17 Mar 2024 02:43

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