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Multilocus sequence typing and porA gene sequencing differentiates strains of Neisseria meningitidis during case clusters

Multilocus sequence typing and porA gene sequencing differentiates strains of Neisseria meningitidis during case clusters
Multilocus sequence typing and porA gene sequencing differentiates strains of Neisseria meningitidis during case clusters
Notified cases of meningococcal disease (MD) in Scotland and many other countries within Europe have increased in recent years 1 and are often associated with epidemic strains such as C:2a:P1.5 from the ET-37 complex. 2 A number of case
clusters due to these strains have occurred in schools, universities and other close-contact situations. 3-5 Characterisation of Neisseria meningitidis strains isolated
during case clusters is important for public health management, and indicates the necessity for molecular techniques to differentiate strains.
Adolescent, Adult, Bacterial Typing Techniques/methods, Disease Outbreaks, Female, Genes, Bacterial, Humans, Infant, Male, Meningitis, Meningococcal/epidemiology, Neisseria meningitidis/classification, Porins/genetics, Scotland/epidemiology
0967-4845
160-162
Clarke, S C
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Diggle, M A
d739c25b-e038-4a9a-850d-2e2fd6ff4a4f
Edwards, G F S
55f29019-4c97-436c-9315-ce8c1737837f
Clarke, S C
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Diggle, M A
d739c25b-e038-4a9a-850d-2e2fd6ff4a4f
Edwards, G F S
55f29019-4c97-436c-9315-ce8c1737837f

Clarke, S C, Diggle, M A and Edwards, G F S (2002) Multilocus sequence typing and porA gene sequencing differentiates strains of Neisseria meningitidis during case clusters. British Journal of Biomedical Science, 59 (3), 160-162. (doi:10.1080/09674845.2002.11978034).

Record type: Article

Abstract

Notified cases of meningococcal disease (MD) in Scotland and many other countries within Europe have increased in recent years 1 and are often associated with epidemic strains such as C:2a:P1.5 from the ET-37 complex. 2 A number of case
clusters due to these strains have occurred in schools, universities and other close-contact situations. 3-5 Characterisation of Neisseria meningitidis strains isolated
during case clusters is important for public health management, and indicates the necessity for molecular techniques to differentiate strains.

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More information

Published date: 2002
Keywords: Adolescent, Adult, Bacterial Typing Techniques/methods, Disease Outbreaks, Female, Genes, Bacterial, Humans, Infant, Male, Meningitis, Meningococcal/epidemiology, Neisseria meningitidis/classification, Porins/genetics, Scotland/epidemiology

Identifiers

Local EPrints ID: 455390
URI: http://eprints.soton.ac.uk/id/eprint/455390
ISSN: 0967-4845
PURE UUID: d645abb4-dd84-488c-8d58-76d7f8d762a1
ORCID for S C Clarke: ORCID iD orcid.org/0000-0002-7009-1548

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Date deposited: 21 Mar 2022 17:31
Last modified: 23 Jul 2022 01:56

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Contributors

Author: S C Clarke ORCID iD
Author: M A Diggle
Author: G F S Edwards

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