Multilocus sequence typing and porA gene sequencing differentiates strains of Neisseria meningitidis during case clusters
Multilocus sequence typing and porA gene sequencing differentiates strains of Neisseria meningitidis during case clusters
Notified cases of meningococcal disease (MD) in Scotland and many other countries within Europe have increased in recent years 1 and are often associated with epidemic strains such as C:2a:P1.5 from the ET-37 complex. 2 A number of case
clusters due to these strains have occurred in schools, universities and other close-contact situations. 3-5 Characterisation of Neisseria meningitidis strains isolated
during case clusters is important for public health management, and indicates the necessity for molecular techniques to differentiate strains.
Adolescent, Adult, Bacterial Typing Techniques/methods, Disease Outbreaks, Female, Genes, Bacterial, Humans, Infant, Male, Meningitis, Meningococcal/epidemiology, Neisseria meningitidis/classification, Porins/genetics, Scotland/epidemiology
160-162
Clarke, S C
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Diggle, M A
d739c25b-e038-4a9a-850d-2e2fd6ff4a4f
Edwards, G F S
55f29019-4c97-436c-9315-ce8c1737837f
2002
Clarke, S C
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Diggle, M A
d739c25b-e038-4a9a-850d-2e2fd6ff4a4f
Edwards, G F S
55f29019-4c97-436c-9315-ce8c1737837f
Clarke, S C, Diggle, M A and Edwards, G F S
(2002)
Multilocus sequence typing and porA gene sequencing differentiates strains of Neisseria meningitidis during case clusters.
British Journal of Biomedical Science, 59 (3), .
(doi:10.1080/09674845.2002.11978034).
Abstract
Notified cases of meningococcal disease (MD) in Scotland and many other countries within Europe have increased in recent years 1 and are often associated with epidemic strains such as C:2a:P1.5 from the ET-37 complex. 2 A number of case
clusters due to these strains have occurred in schools, universities and other close-contact situations. 3-5 Characterisation of Neisseria meningitidis strains isolated
during case clusters is important for public health management, and indicates the necessity for molecular techniques to differentiate strains.
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Published date: 2002
Keywords:
Adolescent, Adult, Bacterial Typing Techniques/methods, Disease Outbreaks, Female, Genes, Bacterial, Humans, Infant, Male, Meningitis, Meningococcal/epidemiology, Neisseria meningitidis/classification, Porins/genetics, Scotland/epidemiology
Identifiers
Local EPrints ID: 455390
URI: http://eprints.soton.ac.uk/id/eprint/455390
ISSN: 0967-4845
PURE UUID: d645abb4-dd84-488c-8d58-76d7f8d762a1
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Date deposited: 21 Mar 2022 17:31
Last modified: 17 Mar 2024 03:07
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Author:
M A Diggle
Author:
G F S Edwards
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