Nucleotide sequence-based typing of bacteria and the impact of automation
Nucleotide sequence-based typing of bacteria and the impact of automation
DNA-based typing methods are increasingly important for the characterisation of bacteria. They are used to monitor the epidemiology of pathogens with public health significance and also to help understand the evolution and population biology of bacteria. However, these methods require accuracy and reproducibility and are often of a high-throughput nature. Laboratory automation is therefore the key to the successful implementation of such methods. This review describes the impact of automation on DNA-based typing methods, particularly multi-locus sequence typing (MLST), and the method components that can be automated.
Automation, Biotechnology/methods, DNA, Bacterial/analysis, Genetic Techniques
858-862
Clarke, Stuart C
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
22 August 2002
Clarke, Stuart C
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Clarke, Stuart C
(2002)
Nucleotide sequence-based typing of bacteria and the impact of automation.
BioEssays, 24 (9), .
(doi:10.1002/bies.10142).
Abstract
DNA-based typing methods are increasingly important for the characterisation of bacteria. They are used to monitor the epidemiology of pathogens with public health significance and also to help understand the evolution and population biology of bacteria. However, these methods require accuracy and reproducibility and are often of a high-throughput nature. Laboratory automation is therefore the key to the successful implementation of such methods. This review describes the impact of automation on DNA-based typing methods, particularly multi-locus sequence typing (MLST), and the method components that can be automated.
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Published date: 22 August 2002
Keywords:
Automation, Biotechnology/methods, DNA, Bacterial/analysis, Genetic Techniques
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Local EPrints ID: 455391
URI: http://eprints.soton.ac.uk/id/eprint/455391
ISSN: 0265-9247
PURE UUID: ba5c564f-882c-4559-abeb-39a05c6185bf
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Date deposited: 21 Mar 2022 17:31
Last modified: 17 Mar 2024 03:07
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