Laboratory confirmation of meningococcal disease in Scotland, 1993-9
Laboratory confirmation of meningococcal disease in Scotland, 1993-9
Aims: to describe the laboratory confirmation of meningococcal disease, using culture and non-culture based techniques, between 1993 and 1999 as part of a national service in Scotland.
Methods: samples from patients with suspected meningococcal disease in Scotland were analysed by culture and non-culture based techniques to gain a laboratory confirmation of disease. Data were analysed to establish the number of disease cases, the serogroups of the organisms involved, and the importance of the techniques used.
Results: between 1993 and 1999, there was a total of 1749 notified cases of meningococcal disease in Scotland. Culture based methods provided a laboratory confirmation of 788 cases whereas non-culture techniques confirmed 461 cases.
Conclusions: non-culture techniques were a useful addition to culture based techniques in Scotland and improved the dataset required for public health management, disease surveillance, and vaccine policy.
Agglutination Tests/methods, Antibodies, Bacterial/blood, Bacterial Typing Techniques/methods, Bacteriological Techniques/methods, Humans, Incidence, Meningococcal Infections/diagnosis, Neisseria meningitidis/classification, Pharynx/microbiology, Polymerase Chain Reaction, Scotland
32-36
Clarke, S.C.
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Reid, J.
820bf5a8-ad5b-40c6-b4ea-23ecbbbf6e71
Thom, L.
9ea500f0-d6bb-404b-b6eb-0c55158b968a
Denham, B.C.
3c56a021-3555-45d8-b840-137c83241878
Edwards, G.F.S.
55f29019-4c97-436c-9315-ce8c1737837f
1 January 2002
Clarke, S.C.
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Reid, J.
820bf5a8-ad5b-40c6-b4ea-23ecbbbf6e71
Thom, L.
9ea500f0-d6bb-404b-b6eb-0c55158b968a
Denham, B.C.
3c56a021-3555-45d8-b840-137c83241878
Edwards, G.F.S.
55f29019-4c97-436c-9315-ce8c1737837f
Clarke, S.C., Reid, J., Thom, L., Denham, B.C. and Edwards, G.F.S.
(2002)
Laboratory confirmation of meningococcal disease in Scotland, 1993-9.
Journal of Clinical Pathology, 55 (1), .
Abstract
Aims: to describe the laboratory confirmation of meningococcal disease, using culture and non-culture based techniques, between 1993 and 1999 as part of a national service in Scotland.
Methods: samples from patients with suspected meningococcal disease in Scotland were analysed by culture and non-culture based techniques to gain a laboratory confirmation of disease. Data were analysed to establish the number of disease cases, the serogroups of the organisms involved, and the importance of the techniques used.
Results: between 1993 and 1999, there was a total of 1749 notified cases of meningococcal disease in Scotland. Culture based methods provided a laboratory confirmation of 788 cases whereas non-culture techniques confirmed 461 cases.
Conclusions: non-culture techniques were a useful addition to culture based techniques in Scotland and improved the dataset required for public health management, disease surveillance, and vaccine policy.
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More information
Accepted/In Press date: 18 July 2001
Published date: 1 January 2002
Keywords:
Agglutination Tests/methods, Antibodies, Bacterial/blood, Bacterial Typing Techniques/methods, Bacteriological Techniques/methods, Humans, Incidence, Meningococcal Infections/diagnosis, Neisseria meningitidis/classification, Pharynx/microbiology, Polymerase Chain Reaction, Scotland
Identifiers
Local EPrints ID: 455393
URI: http://eprints.soton.ac.uk/id/eprint/455393
ISSN: 0021-9746
PURE UUID: cb2e6c72-b5de-4598-ad55-fd4bb3b536fa
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Date deposited: 21 Mar 2022 17:31
Last modified: 17 Mar 2024 03:07
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Contributors
Author:
J. Reid
Author:
L. Thom
Author:
B.C. Denham
Author:
G.F.S. Edwards
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