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Laboratory confirmation of meningococcal disease in Scotland, 1993-9

Laboratory confirmation of meningococcal disease in Scotland, 1993-9
Laboratory confirmation of meningococcal disease in Scotland, 1993-9

AIMS: To describe the laboratory confirmation of meningococcal disease, using culture and non-culture based techniques, between 1993 and 1999 as part of a national service in Scotland.

METHODS: Samples from patients with suspected meningococcal disease in Scotland were analysed by culture and non-culture based techniques to gain a laboratory confirmation of disease. Data were analysed to establish the number of disease cases, the serogroups of the organisms involved, and the importance of the techniques used.

RESULTS: Between 1993 and 1999, there was a total of 1749 notified cases of meningococcal disease in Scotland. Culture based methods provided a laboratory confirmation of 788 cases whereas non-culture techniques confirmed 461 cases.

CONCLUSIONS: Non-culture techniques were a useful addition to culture based techniques in Scotland and improved the dataset required for public health management, disease surveillance, and vaccine policy.

Agglutination Tests/methods, Antibodies, Bacterial/blood, Bacterial Typing Techniques/methods, Bacteriological Techniques/methods, Humans, Incidence, Meningococcal Infections/diagnosis, Neisseria meningitidis/classification, Pharynx/microbiology, Polymerase Chain Reaction, Scotland
0021-9746
32-36
Clarke, S C
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Reid, J
820bf5a8-ad5b-40c6-b4ea-23ecbbbf6e71
Thom, L
9ea500f0-d6bb-404b-b6eb-0c55158b968a
Denham, B C
3c56a021-3555-45d8-b840-137c83241878
Edwards, G F S
55f29019-4c97-436c-9315-ce8c1737837f
Clarke, S C
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Reid, J
820bf5a8-ad5b-40c6-b4ea-23ecbbbf6e71
Thom, L
9ea500f0-d6bb-404b-b6eb-0c55158b968a
Denham, B C
3c56a021-3555-45d8-b840-137c83241878
Edwards, G F S
55f29019-4c97-436c-9315-ce8c1737837f

Clarke, S C, Reid, J, Thom, L, Denham, B C and Edwards, G F S (2002) Laboratory confirmation of meningococcal disease in Scotland, 1993-9. Journal of Clinical Pathology, 55 (1), 32-36.

Record type: Article

Abstract

AIMS: To describe the laboratory confirmation of meningococcal disease, using culture and non-culture based techniques, between 1993 and 1999 as part of a national service in Scotland.

METHODS: Samples from patients with suspected meningococcal disease in Scotland were analysed by culture and non-culture based techniques to gain a laboratory confirmation of disease. Data were analysed to establish the number of disease cases, the serogroups of the organisms involved, and the importance of the techniques used.

RESULTS: Between 1993 and 1999, there was a total of 1749 notified cases of meningococcal disease in Scotland. Culture based methods provided a laboratory confirmation of 788 cases whereas non-culture techniques confirmed 461 cases.

CONCLUSIONS: Non-culture techniques were a useful addition to culture based techniques in Scotland and improved the dataset required for public health management, disease surveillance, and vaccine policy.

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More information

Published date: January 2002
Keywords: Agglutination Tests/methods, Antibodies, Bacterial/blood, Bacterial Typing Techniques/methods, Bacteriological Techniques/methods, Humans, Incidence, Meningococcal Infections/diagnosis, Neisseria meningitidis/classification, Pharynx/microbiology, Polymerase Chain Reaction, Scotland

Identifiers

Local EPrints ID: 455393
URI: http://eprints.soton.ac.uk/id/eprint/455393
ISSN: 0021-9746
PURE UUID: cb2e6c72-b5de-4598-ad55-fd4bb3b536fa
ORCID for S C Clarke: ORCID iD orcid.org/0000-0002-7009-1548

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Date deposited: 21 Mar 2022 17:31
Last modified: 23 Jul 2022 01:56

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Contributors

Author: S C Clarke ORCID iD
Author: J Reid
Author: L Thom
Author: B C Denham
Author: G F S Edwards

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