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Genetic relatedness of antibiotic-resistant pneumococci isolated during case clusters

Genetic relatedness of antibiotic-resistant pneumococci isolated during case clusters
Genetic relatedness of antibiotic-resistant pneumococci isolated during case clusters

Multilocus sequence typing of Streptococcus pneumoniae associated with two case clusters of disease is reported here for the first time. Isolates from the first cluster were serotype 19F, resistant to penicillin and erythromycin, and were characterized as ST 320. Isolates from the second cluster were serogroup 4, resistant to ciprofloxacin, and were characterized as ST 206. Therefore, the isolates from these clusters were antibiotic-resistant, of serotypes infrequently isolated, and of uncommon sequence types.

Anti-Bacterial Agents/pharmacology, Bacterial Typing Techniques, Blood/microbiology, Ciprofloxacin/pharmacology, DNA, Bacterial/chemistry, Drug Resistance, Bacterial, Erythromycin/pharmacology, Genotype, Humans, Microbial Sensitivity Tests, Penicillins/pharmacology, Pneumococcal Infections/microbiology, Sequence Analysis, DNA, Serotyping, Sputum/microbiology, Streptococcus pneumoniae/classification
0022-2615
1097-1099
Clarke, S C
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Lawrie, D
cb1faba4-1a7f-41e2-84af-6e39360b3ae9
Diggle, M A
d739c25b-e038-4a9a-850d-2e2fd6ff4a4f
Clarke, S C
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Lawrie, D
cb1faba4-1a7f-41e2-84af-6e39360b3ae9
Diggle, M A
d739c25b-e038-4a9a-850d-2e2fd6ff4a4f

Clarke, S C, Lawrie, D and Diggle, M A (2004) Genetic relatedness of antibiotic-resistant pneumococci isolated during case clusters. Journal of Medical Microbiology, 53 (Pt 11), 1097-1099. (doi:10.1099/jmm.0.45733-0).

Record type: Article

Abstract

Multilocus sequence typing of Streptococcus pneumoniae associated with two case clusters of disease is reported here for the first time. Isolates from the first cluster were serotype 19F, resistant to penicillin and erythromycin, and were characterized as ST 320. Isolates from the second cluster were serogroup 4, resistant to ciprofloxacin, and were characterized as ST 206. Therefore, the isolates from these clusters were antibiotic-resistant, of serotypes infrequently isolated, and of uncommon sequence types.

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More information

Published date: November 2004
Keywords: Anti-Bacterial Agents/pharmacology, Bacterial Typing Techniques, Blood/microbiology, Ciprofloxacin/pharmacology, DNA, Bacterial/chemistry, Drug Resistance, Bacterial, Erythromycin/pharmacology, Genotype, Humans, Microbial Sensitivity Tests, Penicillins/pharmacology, Pneumococcal Infections/microbiology, Sequence Analysis, DNA, Serotyping, Sputum/microbiology, Streptococcus pneumoniae/classification

Identifiers

Local EPrints ID: 455397
URI: http://eprints.soton.ac.uk/id/eprint/455397
ISSN: 0022-2615
PURE UUID: dc6abcba-fba4-4a46-a7d2-147c707e06a0
ORCID for S C Clarke: ORCID iD orcid.org/0000-0002-7009-1548

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Date deposited: 21 Mar 2022 17:32
Last modified: 17 Mar 2024 03:07

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Contributors

Author: S C Clarke ORCID iD
Author: D Lawrie
Author: M A Diggle

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