Vaccine preventable meningitis in Malaysia: epidemiology and management
Vaccine preventable meningitis in Malaysia: epidemiology and management
Worldwide bacterial meningitis accounts for more than one million cases and 135,000 deaths annually. Profound, lasting neurological complications occur in 9-25% of cases. This review confirms the greatest risk from bacterial meningitis is in early life in Malaysia. Much of the disease burden can be avoided by immunization, particularly against Haemophilus influenzae type b (Hib) and Streptococcus pneumoniae. Despite inclusion of the Hib vaccine in the National Immunisation Programme and the licensure of pneumococcal vaccines, these two species are the main contributors to bacterial meningitis in Malaysia, with Neisseria meningitidis and Mycobacterium tuberculosis, causing a smaller proportion of disease. The high Hib prevalence may partly be due to dated, small-scale studies limiting the understanding of the current epidemiological situation. This highlights the need for larger, better quality surveillance from Malaysia to evaluate the success of Hib immunization and to help guide immunization policy for vaccines against S. pneumoniae and N. meningitidis.
Age Factors, Bacterial Capsules, Cost of Illness, Disease Management, Haemophilus Vaccines/therapeutic use, Haemophilus influenzae type b, Humans, Immunization Programs, Malaysia/epidemiology, Meningitis, Bacterial/classification, Pneumococcal Vaccines/therapeutic use, Streptococcus pneumoniae, Vaccination
705-714
McNeil, Hannah C
ca06cd91-3005-4321-858b-bab81da76ab4
Jefferies, Johanna M C
942356b7-2070-49ad-9376-cde03c5fe13d
Clarke, Stuart C
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
1 June 2015
McNeil, Hannah C
ca06cd91-3005-4321-858b-bab81da76ab4
Jefferies, Johanna M C
942356b7-2070-49ad-9376-cde03c5fe13d
Clarke, Stuart C
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
McNeil, Hannah C, Jefferies, Johanna M C and Clarke, Stuart C
(2015)
Vaccine preventable meningitis in Malaysia: epidemiology and management.
Expert Review of Anti-Infective Therapy, 13 (6), .
(doi:10.1586/14787210.2015.1033401).
Abstract
Worldwide bacterial meningitis accounts for more than one million cases and 135,000 deaths annually. Profound, lasting neurological complications occur in 9-25% of cases. This review confirms the greatest risk from bacterial meningitis is in early life in Malaysia. Much of the disease burden can be avoided by immunization, particularly against Haemophilus influenzae type b (Hib) and Streptococcus pneumoniae. Despite inclusion of the Hib vaccine in the National Immunisation Programme and the licensure of pneumococcal vaccines, these two species are the main contributors to bacterial meningitis in Malaysia, with Neisseria meningitidis and Mycobacterium tuberculosis, causing a smaller proportion of disease. The high Hib prevalence may partly be due to dated, small-scale studies limiting the understanding of the current epidemiological situation. This highlights the need for larger, better quality surveillance from Malaysia to evaluate the success of Hib immunization and to help guide immunization policy for vaccines against S. pneumoniae and N. meningitidis.
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e-pub ahead of print date: 11 May 2015
Published date: 1 June 2015
Keywords:
Age Factors, Bacterial Capsules, Cost of Illness, Disease Management, Haemophilus Vaccines/therapeutic use, Haemophilus influenzae type b, Humans, Immunization Programs, Malaysia/epidemiology, Meningitis, Bacterial/classification, Pneumococcal Vaccines/therapeutic use, Streptococcus pneumoniae, Vaccination
Identifiers
Local EPrints ID: 455550
URI: http://eprints.soton.ac.uk/id/eprint/455550
ISSN: 1744-8336
PURE UUID: 48db110c-c74e-419c-83f1-d338f0175f39
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Date deposited: 25 Mar 2022 17:35
Last modified: 17 Mar 2024 03:07
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Author:
Hannah C McNeil
Author:
Johanna M C Jefferies
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