READ ME File For �Dataset supporting a doctoral thesis entitled 'A Correlative X-ray and Electron Microscopy Framework for 3D Bone Imaging and its application to Bone Development and Disease in Human and Animal Tissue' Dataset DOI: 10.5258/SOTON/D2118 Author: PATRICIA GOGGIN, University of Southampton, p.goggin@soton.ac.uk, ORCID ID 0000-0003-4730-0206 This dataset supports the thesis entitled: 'A Correlative X-ray and Electron Microscopy Framework for 3D Bone Imaging and its application to Bone Development and Disease in Human and Animal Tissue� AWARDED BY: University of Southampton DATE OF AWARD: 2022 DESCRIPTION OF THE DATA [This should include a detailed description of the data, how it was collected/created, any specialist software needed to view the data] This dataset contains: X-ray �CT .txm recon files collected using Xradia Versa 510 �CT scanner. Complete raw data files are available on request. Representative parts of serial block face scanning electron microscopy datasets collected using 3View on a ThermoFisher Quanta 250 FEGSEM. Complete datasets are available on request. KEY R18_263 MOUSE ADULT R18_266 MOUSE JUVENILE R18_264 MOUSE ADULT R18_267 MOUSE JUVENILE R18_265 MOUSE ADULT R18_268 MOUSE JUVENILE R19_528 OSTEOARTHRITIS HUMAN R19_531 OSTEOPOROSIS HUMAN R19_599 OSTEOARTHRITIS HUMAN R19_532 OSTEOPOROSIS HUMAN R19_530 OSTEOARTHRITIS HUMAN R19_533 OSTEOPOROSIS HUMAN Date of data collection: 2018-2019 Information about geographic location of data collection: Southampton, UK Licence: CC BY Related projects/Funders: Work funded by the Institute for Life Sciences and the Faculty of Engineering and Physical Sciences, University of Southampton Related publications: High-resolution 3D imaging of osteocytes and computational modelling in mechanobiology: insights on bone development, ageing, health and disease, Eur Cell Mater, 2016 Development of protocols for the first serial block-face scanning electron microscopy (SBF SEM) studies of bone tissue, Bone 2020 Date that the file was created: Jan, 2022