Discrete choice experiment exploring women's preferences in a novel device designed to monitor the womb environment and improve our understanding of reproductive disorders
Discrete choice experiment exploring women's preferences in a novel device designed to monitor the womb environment and improve our understanding of reproductive disorders
Objectives The study aims to determine the relative importance of key attributes of a novel intrauterine device. The device monitors uterine oxygen, pH and temperature in real time with the aim of improving our understanding and treatment of reproductive disorders. Design A discrete choice experiment was used to elicit preferences in this novel investigative tool. The attributes and levels used in the choice scenarios were length of time using the device (7, 14 or 28 days), information obtained to guide treatment (limited, majority or all cases), risk of complications (1% or 10%) and discreteness (completely discrete, moderately discrete or indiscrete). Setting Secondary care hospital in Hampshire, UK. Participants 361 women of reproductive age. Primary and secondary outcome measures Conditional logit and latent class logit regression models to determine the preference for each attribute. Results Conditional logit coefficients allow comparison between attributes; women placed most importance on obtaining information to guide treatment in all cases (2.771), followed by having a completely discrete device (1.104), reducing risk of complications by 1% (0.184) and decreased length of time by 1 day (0.0150). All coefficients p<0.01. Latent class conditional logit assigns participants to two classes with 27.4% in class 1 who are less likely to have higher education or qualify for National Health Service-funded in vitro fertilisation compared with class 2. Those in class 2 placed 1.7 times more importance on a device whose information guided treatment in all cases and a 1% decrease in complications risk was nearly 15 times more attractive. Conclusions Women placed most importance on having a device that obtains information to guide treatment and are willing to use the device for a longer, have a device with higher risk of complications and an indiscrete device if it is able to provide answers and direction for treatment of their reproductive disorder.
gynaecology, health economics, reproductive medicine, subfertility
e058419
Ng, Ka Ying Bonnie
869b3b2d-dd7c-407d-88aa-5db399e02b3a
Evans, Rhiannon
1b0ffa06-de90-43a9-a240-1c6ac05f1f0d
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Mentzakis, Emmanouil
c0922185-18c7-49c2-a659-8ee6d89b5d74
Cheong, Ying C.
4efbba2a-3036-4dce-82f1-8b4017952c83
29 April 2022
Ng, Ka Ying Bonnie
869b3b2d-dd7c-407d-88aa-5db399e02b3a
Evans, Rhiannon
1b0ffa06-de90-43a9-a240-1c6ac05f1f0d
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Mentzakis, Emmanouil
c0922185-18c7-49c2-a659-8ee6d89b5d74
Cheong, Ying C.
4efbba2a-3036-4dce-82f1-8b4017952c83
Ng, Ka Ying Bonnie, Evans, Rhiannon, Morgan, Hywel, Mentzakis, Emmanouil and Cheong, Ying C.
(2022)
Discrete choice experiment exploring women's preferences in a novel device designed to monitor the womb environment and improve our understanding of reproductive disorders.
BMJ Open, 12 (4), , [e058419].
(doi:10.1136/bmjopen-2021-058419).
Abstract
Objectives The study aims to determine the relative importance of key attributes of a novel intrauterine device. The device monitors uterine oxygen, pH and temperature in real time with the aim of improving our understanding and treatment of reproductive disorders. Design A discrete choice experiment was used to elicit preferences in this novel investigative tool. The attributes and levels used in the choice scenarios were length of time using the device (7, 14 or 28 days), information obtained to guide treatment (limited, majority or all cases), risk of complications (1% or 10%) and discreteness (completely discrete, moderately discrete or indiscrete). Setting Secondary care hospital in Hampshire, UK. Participants 361 women of reproductive age. Primary and secondary outcome measures Conditional logit and latent class logit regression models to determine the preference for each attribute. Results Conditional logit coefficients allow comparison between attributes; women placed most importance on obtaining information to guide treatment in all cases (2.771), followed by having a completely discrete device (1.104), reducing risk of complications by 1% (0.184) and decreased length of time by 1 day (0.0150). All coefficients p<0.01. Latent class conditional logit assigns participants to two classes with 27.4% in class 1 who are less likely to have higher education or qualify for National Health Service-funded in vitro fertilisation compared with class 2. Those in class 2 placed 1.7 times more importance on a device whose information guided treatment in all cases and a 1% decrease in complications risk was nearly 15 times more attractive. Conclusions Women placed most importance on having a device that obtains information to guide treatment and are willing to use the device for a longer, have a device with higher risk of complications and an indiscrete device if it is able to provide answers and direction for treatment of their reproductive disorder.
Text
DCE BMJ Open CLEAN
- Accepted Manuscript
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e058419.full
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More information
Accepted/In Press date: 8 April 2022
e-pub ahead of print date: 29 April 2022
Published date: 29 April 2022
Additional Information:
Funding Information:
Funding This study has been funded by the NIHR i4i Innovation grant (grant number II-LB-0715-20002) awarded to YCC.
Publisher Copyright:
© Author(s) (or their employer(s)) 2022.
Keywords:
gynaecology, health economics, reproductive medicine, subfertility
Identifiers
Local EPrints ID: 456597
URI: http://eprints.soton.ac.uk/id/eprint/456597
ISSN: 2044-6055
PURE UUID: 65d95a8b-112c-4df1-a669-fd6629b8690d
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Date deposited: 05 May 2022 16:45
Last modified: 17 Mar 2024 03:28
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Contributors
Author:
Ka Ying Bonnie Ng
Author:
Rhiannon Evans
Author:
Hywel Morgan
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