[68Ga]Ga-THP-Pam: A PET radiotracer for imaging vascular calcification
[68Ga]Ga-THP-Pam: A PET radiotracer for imaging vascular calcification
[68Ga]Ga-THP-Pam was previously demonstrated to have high affinity towards a number ofcalcium salts while [18F]NaF, the most used PET radiotracer for bone imaging has highaffinity only for hydroxyapatite (the main component of bone mineral).1 It was hypothesisedthat the broad calcium mineral affinity of [68Ga]Ga-THP-Pam may be advantageous indetection of vascular calcification (VC), where the composition of solid calcium mineral maybe more varied than the composition of bone.2 A direct comparison of [68Ga]Ga-THP-Pamand [18F]NaF in a rat model of VC was performed to test this hypothesis.
Keeling, George
46b88157-716d-4670-ace2-72dc90d13c69
Baark, Friedrich
95fee8d8-1e1e-4dea-a5a4-4304456a53cd
Katsamenis, Orestis
8553e7c3-d860-4b7a-a883-abf6c0c4b438
Reader, Andrew
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Smith, Gareth
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Terry, Samantha
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Blower, Philip
bab2bda7-a8cb-481c-b9e8-9ebcb2a8d3b4
de Rosales, Rafae l Torres Martin
97eaa65b-7299-4270-874d-f2218138a685
June 2021
Keeling, George
46b88157-716d-4670-ace2-72dc90d13c69
Baark, Friedrich
95fee8d8-1e1e-4dea-a5a4-4304456a53cd
Katsamenis, Orestis
8553e7c3-d860-4b7a-a883-abf6c0c4b438
Reader, Andrew
5fecf0c3-2319-4b12-bc7a-03d926139b67
Smith, Gareth
0c0406a6-d657-424d-a0ff-831ec325ff4d
Terry, Samantha
37cba847-09e6-4e9a-bc8b-b91b7c573727
Blower, Philip
bab2bda7-a8cb-481c-b9e8-9ebcb2a8d3b4
de Rosales, Rafae l Torres Martin
97eaa65b-7299-4270-874d-f2218138a685
Keeling, George, Baark, Friedrich, Katsamenis, Orestis, Reader, Andrew, Smith, Gareth, Terry, Samantha, Blower, Philip and de Rosales, Rafae l Torres Martin
(2021)
[68Ga]Ga-THP-Pam: A PET radiotracer for imaging vascular calcification.
World Molecular Imaging Congress, Miami Beach Convention Centre, Miami, United States.
06 - 09 Oct 2021.
Record type:
Conference or Workshop Item
(Paper)
Abstract
[68Ga]Ga-THP-Pam was previously demonstrated to have high affinity towards a number ofcalcium salts while [18F]NaF, the most used PET radiotracer for bone imaging has highaffinity only for hydroxyapatite (the main component of bone mineral).1 It was hypothesisedthat the broad calcium mineral affinity of [68Ga]Ga-THP-Pam may be advantageous indetection of vascular calcification (VC), where the composition of solid calcium mineral maybe more varied than the composition of bone.2 A direct comparison of [68Ga]Ga-THP-Pamand [18F]NaF in a rat model of VC was performed to test this hypothesis.
Text
GPK WMIC THP-Pam Abstract FINAL
- Accepted Manuscript
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Published date: June 2021
Venue - Dates:
World Molecular Imaging Congress, Miami Beach Convention Centre, Miami, United States, 2021-10-06 - 2021-10-09
Identifiers
Local EPrints ID: 456702
URI: http://eprints.soton.ac.uk/id/eprint/456702
PURE UUID: fc62d01e-9677-497f-acfa-aa6f401affe0
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Date deposited: 09 May 2022 17:16
Last modified: 17 Mar 2024 03:24
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Contributors
Author:
George Keeling
Author:
Friedrich Baark
Author:
Andrew Reader
Author:
Gareth Smith
Author:
Samantha Terry
Author:
Philip Blower
Author:
Rafae l Torres Martin de Rosales
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