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Review of open cavity random lasers as laser-based sensors

Review of open cavity random lasers as laser-based sensors
Review of open cavity random lasers as laser-based sensors
In this review, the concept of open cavity lasing for ultrasensitive sensing is explored, specifically in driving important innovations as laser-based biosensors─a field mostly dominated by fluorescence-based sensing. Laser-based sensing exhibits higher signal amplification and lower signal-to-noise ratio due to narrow emission lines as well as high sensitivity due to nonlinear components. The versatility of open cavity random lasers for probing analytes directly which is ultrasensitive to small changes in chemical composition and temperature fluctuations paves the path of utilizing narrow emission lines for advanced sensing. The concept of random lasing is first explained followed by a comparison of the different lasing threshold that has been reported. This is followed by a survey of reports on laser-based sensing and more specifically as biosensors. Finally, a perspective on the way forward for open cavity laser-based sensing is put forth.
Huntington's disease detection, biosensor, brain tissue detection, cancer detection, fiber random laser, flexible laser, laser-based sensing, random laser
2379-3694
914-928
Azmi, Atiqah Nabieha
0bb75764-40ce-4cbf-94a7-3a350c22e6b4
Wan Ismail, Wan Zakiah
86b29da4-0e0f-4bc2-a603-5fb929f072c6
Abu Hassan, Haslan
5b9d832e-7a23-4c30-ad7b-e49abd6c37e2
Halim, Mohd Mahadi
ad22a0b4-36fa-4c11-a97b-12ca3f886bcc
Zainal, Norzaini
4c93550f-61c6-445c-a325-78f7386aee75
Muskens, Otto L
2284101a-f9ef-4d79-8951-a6cda5bfc7f9
Wan Ahmad Kamil, Wan Maryam
261005c8-c6f4-46a7-85b8-ec1d16addc45
Azmi, Atiqah Nabieha
0bb75764-40ce-4cbf-94a7-3a350c22e6b4
Wan Ismail, Wan Zakiah
86b29da4-0e0f-4bc2-a603-5fb929f072c6
Abu Hassan, Haslan
5b9d832e-7a23-4c30-ad7b-e49abd6c37e2
Halim, Mohd Mahadi
ad22a0b4-36fa-4c11-a97b-12ca3f886bcc
Zainal, Norzaini
4c93550f-61c6-445c-a325-78f7386aee75
Muskens, Otto L
2284101a-f9ef-4d79-8951-a6cda5bfc7f9
Wan Ahmad Kamil, Wan Maryam
261005c8-c6f4-46a7-85b8-ec1d16addc45

Azmi, Atiqah Nabieha, Wan Ismail, Wan Zakiah, Abu Hassan, Haslan, Halim, Mohd Mahadi, Zainal, Norzaini, Muskens, Otto L and Wan Ahmad Kamil, Wan Maryam (2022) Review of open cavity random lasers as laser-based sensors. ACS Sensors, 7 (4), 914-928. (doi:10.1021/acssensors.1c02749).

Record type: Review

Abstract

In this review, the concept of open cavity lasing for ultrasensitive sensing is explored, specifically in driving important innovations as laser-based biosensors─a field mostly dominated by fluorescence-based sensing. Laser-based sensing exhibits higher signal amplification and lower signal-to-noise ratio due to narrow emission lines as well as high sensitivity due to nonlinear components. The versatility of open cavity random lasers for probing analytes directly which is ultrasensitive to small changes in chemical composition and temperature fluctuations paves the path of utilizing narrow emission lines for advanced sensing. The concept of random lasing is first explained followed by a comparison of the different lasing threshold that has been reported. This is followed by a survey of reports on laser-based sensing and more specifically as biosensors. Finally, a perspective on the way forward for open cavity laser-based sensing is put forth.

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More information

e-pub ahead of print date: 4 April 2022
Published date: 22 April 2022
Additional Information: Funding Information: This work was supported by Kementerian Pendidikan Malaysia through Fundamental Research Grant Scheme (FRGS) under account number: FRGS/1/2018/STG02/USM/02/6. Publisher Copyright: © 2022 American Chemical Society. All rights reserved. Copyright: Copyright 2022 Elsevier B.V., All rights reserved.
Keywords: Huntington's disease detection, biosensor, brain tissue detection, cancer detection, fiber random laser, flexible laser, laser-based sensing, random laser

Identifiers

Local EPrints ID: 457020
URI: http://eprints.soton.ac.uk/id/eprint/457020
ISSN: 2379-3694
PURE UUID: 482aaee9-1349-461e-8c0c-871b0c1ad22a
ORCID for Otto L Muskens: ORCID iD orcid.org/0000-0003-0693-5504

Catalogue record

Date deposited: 19 May 2022 16:46
Last modified: 20 May 2022 01:39

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Contributors

Author: Atiqah Nabieha Azmi
Author: Wan Zakiah Wan Ismail
Author: Haslan Abu Hassan
Author: Mohd Mahadi Halim
Author: Norzaini Zainal
Author: Otto L Muskens ORCID iD
Author: Wan Maryam Wan Ahmad Kamil

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