READ ME File For 'Raw Data for A SARS-CoV-2 sensor based on upconversion nanoparticles and graphene oxide' Dataset DOI: 10.5258/SOTON/D2242 ReadMe Author: Maria Eleni Kyriazi, University of Southampton This dataset supports the publication: "A SARS-CoV-2 sensor based on upconversion nanoparticles and graphene oxide" Contents All experimental data recorded and used to generate the above title manuscript which has been accepted for publication to RSC Advances. In particular the dataset contains the data recorded to generate the following figures included in the publication. The figures are as follows: Fig. 1: Representative TEM images (A and B) of core and core shell UCNPs alopng with their corresponding size dustribution histograms (C and D) Fig. 2: Fluorescence emission spectrum of oligonucleotide-coated UCNPs in the presence of increasing GO concentrations (A). Decreasing fluorescence emission at lamda (max) vs increasing GO concentration (B) Fig. 3: Fluorescence emission of oligonucleotide-coated UCNPs after incubation with increasing concentrations of cDNA in the presence of GO (A). Decreasing fluorescence emission at lamda (max) vs increasing cDNA concentration (B) Fig. 4: Fluorescence emission of oligonucleotide-coated UCNPs after incubation with increasing concentrations of cDNA and GO in saliva Fig. 5: Fluoresence emission of oligonucleotise-coated UCNPs in the presence of increasing concentrations of non-complementary DNA Fig. S1: Fluorescence emission spectra of core and core shell UCNPs Fig. S2: Zeta potential measurements of PAA and oligonucleotide-coated UCNPs Fig S3: FTIR measurements of OA, PAA and oligonucleotide-coated UCNPs Fig S4: Representative UV-Vis spectrum of GO Fig. S5: Fluorescence emission of oligonucleotide-coated UCNPs after incubation with increasing concentrations of cRNA in the presence of GO (A). Decreasing fluorescence emission at lamda (max) vs increasing cRNA concentration (B) Geographic location of data collection: University of Southampton, U.K. Related projects: BBSRC (Grant No. BB/N021150/1) Dataset available under a CC BY 4.0 licence Publisher: University of Southampton, U.K. Date: June 2022