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A fully integrated biosensing platform combining acoustofluidics and electromagnetic metamaterials

A fully integrated biosensing platform combining acoustofluidics and electromagnetic metamaterials
A fully integrated biosensing platform combining acoustofluidics and electromagnetic metamaterials
A key challenge in biosensing technology is to develop integrated approaches with the multiple capabilities of bio-sampling, fluid manipulation, high-precision detection and wireless operation. In this work, we present a new concept of integrated biosensing technology using the functionalities of electromagnetic metamaterials and acoustofluidic technology onto a single platform. The new concept of using a single structure to perform microfluidic functions at acoustic frequencies and to detect the characteristics of liquid at microwave frequencies will enable the development of improved lab-on-a-chip devices. As a case study, we demonstrated efficient acoustofluidic functions of mixing and pumping using the designed surface acoustic wave (SAW) device on a LiNbO3 substrate in an experimental setup that also allows the measurement of the electromagnetic characteristics of the interdigitated transducer (IDT) pattern of the same device. We demonstrated microfluidic functions at 10-25 MHz. The device also exhibits electromagnetic resonance at 4.4 GHz with a quality factor value of 294. We showed the device can be used for glucose detection with a good sensitivity of 28 MHz/(mg/ml).
acoustofluidics, actuators, metamaterials, piezoelectric materials, sensors, surface acoustic waves
0022-3727
Zahertar, S.
9e9db9c7-0e1e-4d50-99b8-af23e09ab6ae
Wang, Y.
a9a65808-5877-4b40-a9b0-26970d182c83
Tao, R.
08d40ff6-99d4-4017-9f02-a789ec813496
Xie, J.
01c7d7cb-39a4-4698-834c-b4193c10cd08
Fu, Y. Q.
f46fca5b-04cc-4def-b764-11bd5a57f9a4
Torun, H.
6635ce04-57c2-4847-9cce-67ce2425d32b
Zahertar, S.
9e9db9c7-0e1e-4d50-99b8-af23e09ab6ae
Wang, Y.
a9a65808-5877-4b40-a9b0-26970d182c83
Tao, R.
08d40ff6-99d4-4017-9f02-a789ec813496
Xie, J.
01c7d7cb-39a4-4698-834c-b4193c10cd08
Fu, Y. Q.
f46fca5b-04cc-4def-b764-11bd5a57f9a4
Torun, H.
6635ce04-57c2-4847-9cce-67ce2425d32b

Zahertar, S., Wang, Y., Tao, R., Xie, J., Fu, Y. Q. and Torun, H. (2019) A fully integrated biosensing platform combining acoustofluidics and electromagnetic metamaterials. Journal of Physics D: Applied Physics, 52 (48). (doi:10.1088/1361-6463/ab3f7d).

Record type: Article

Abstract

A key challenge in biosensing technology is to develop integrated approaches with the multiple capabilities of bio-sampling, fluid manipulation, high-precision detection and wireless operation. In this work, we present a new concept of integrated biosensing technology using the functionalities of electromagnetic metamaterials and acoustofluidic technology onto a single platform. The new concept of using a single structure to perform microfluidic functions at acoustic frequencies and to detect the characteristics of liquid at microwave frequencies will enable the development of improved lab-on-a-chip devices. As a case study, we demonstrated efficient acoustofluidic functions of mixing and pumping using the designed surface acoustic wave (SAW) device on a LiNbO3 substrate in an experimental setup that also allows the measurement of the electromagnetic characteristics of the interdigitated transducer (IDT) pattern of the same device. We demonstrated microfluidic functions at 10-25 MHz. The device also exhibits electromagnetic resonance at 4.4 GHz with a quality factor value of 294. We showed the device can be used for glucose detection with a good sensitivity of 28 MHz/(mg/ml).

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More information

Published date: 17 September 2019
Additional Information: © 2019 IOP Publishing Ltd
Keywords: acoustofluidics, actuators, metamaterials, piezoelectric materials, sensors, surface acoustic waves

Identifiers

Local EPrints ID: 457760
URI: http://eprints.soton.ac.uk/id/eprint/457760
ISSN: 0022-3727
PURE UUID: 43b3b9ab-a75d-4ac9-9aad-a67dc8373208
ORCID for S. Zahertar: ORCID iD orcid.org/0000-0001-6988-2345

Catalogue record

Date deposited: 16 Jun 2022 16:32
Last modified: 17 Mar 2024 04:08

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Contributors

Author: S. Zahertar ORCID iD
Author: Y. Wang
Author: R. Tao
Author: J. Xie
Author: Y. Q. Fu
Author: H. Torun

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