Metabolism of the early embryo: energy production and utilization
Metabolism of the early embryo: energy production and utilization
The vast majority of studies on early mammalian embryo metabolism have been concerned with the generation, rather than the fate, of ATP. Thus, research has focused on the uptake or metabolism of energy sources added to embryo culture media. There have been an even greater number of studies in which metabolism as such has not been measured, but rather where blastocyst formation has been used as an endpoint to assess the effect of different energy sourees. It is generally agreed that the early phases of mammalian preimplantation development are relatively quiescent metabolically, relying on substrates such as pyruvate, lactate, or amino acids, which are metabolized aerobically (1–5).
61-68
Leese, H.J.
1f369c23-4361-4534-a093-54699ec5eceb
Houghton, F.D.
53946041-127e-45a8-9edb-bf4b3c23005f
Macmillan, D.A.
377d75bd-4df2-44fd-9e45-9db682c277b4
Donnay, I.
23492c7d-977f-450b-a3d1-7b75ec40e8da
2001
Leese, H.J.
1f369c23-4361-4534-a093-54699ec5eceb
Houghton, F.D.
53946041-127e-45a8-9edb-bf4b3c23005f
Macmillan, D.A.
377d75bd-4df2-44fd-9e45-9db682c277b4
Donnay, I.
23492c7d-977f-450b-a3d1-7b75ec40e8da
Leese, H.J., Houghton, F.D., Macmillan, D.A. and Donnay, I.
(2001)
Metabolism of the early embryo: energy production and utilization.
In,
ART and the Human Blastocyst.
New York.
Springer, .
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Book Section
Abstract
The vast majority of studies on early mammalian embryo metabolism have been concerned with the generation, rather than the fate, of ATP. Thus, research has focused on the uptake or metabolism of energy sources added to embryo culture media. There have been an even greater number of studies in which metabolism as such has not been measured, but rather where blastocyst formation has been used as an endpoint to assess the effect of different energy sourees. It is generally agreed that the early phases of mammalian preimplantation development are relatively quiescent metabolically, relying on substrates such as pyruvate, lactate, or amino acids, which are metabolized aerobically (1–5).
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Published date: 2001
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Copyright: Springer-Verlag New York, Inc. 2001
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Local EPrints ID: 457905
URI: http://eprints.soton.ac.uk/id/eprint/457905
PURE UUID: 324d2f68-9e9c-4e53-b43e-d0b46a32de5e
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Date deposited: 21 Jun 2022 18:19
Last modified: 17 Mar 2024 03:05
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Contributors
Author:
H.J. Leese
Author:
D.A. Macmillan
Author:
I. Donnay
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