The University of Southampton
University of Southampton Institutional Repository

A radiological survey of Paget's disease of bone

A radiological survey of Paget's disease of bone
A radiological survey of Paget's disease of bone

An epidemiological survey of Paget's disease of bone in 14 British towns, selected according to hospital discharge and mortality data for Paget's disease, has shown a range of prevalence s from 4.20' tip to 7.5 of patients aged 55 or more referred to hospital. There was a concentration of high prevalence in Lancashire totrrts. The survey revealed 1223 patients with Paget's disease, and their K-rays have been analysed for the extent and distribution of skeletal involvement. 90' show disease in the pelvis, lumbar spine and upper ends of the femora, and 31c6 have monostotic disease. Males arc more frequently affected than females. Prevalence and extent of the disease rise with age. Greater involvement of the lower limb than the upper limb, a right sided tendency in the limb girdles, and preferential involvement of certain regions of the spine all suggest that bone stress may be significant in the pathogenesis. Examination of the request cards, X-ray reports, and clinical response to the report, reveals that 3496 of patients had symptons recorded which -ere referable to their bone disease. The type of initial radiological examination appears to be of little relevance to the prevalence of the bc:1e disease. The onset of symptoms uay occasionally be in tile third decade but is rencrail.y Inter. The Main synp I to ysinns, :nd caala `. cation are pain, deformity, fracture, evidence of malignancy, and (rarely) spinal cord compression. The results of this survey suggest that Paget's disease of bone may be due to absorption of an external agent, and that the bone changes arc related to bone stress.

University of Southampton
Guyer, Peter Brett
Guyer, Peter Brett

Guyer, Peter Brett (1977) A radiological survey of Paget's disease of bone. University of Southampton, Doctoral Thesis.

Record type: Thesis (Doctoral)

Abstract

An epidemiological survey of Paget's disease of bone in 14 British towns, selected according to hospital discharge and mortality data for Paget's disease, has shown a range of prevalence s from 4.20' tip to 7.5 of patients aged 55 or more referred to hospital. There was a concentration of high prevalence in Lancashire totrrts. The survey revealed 1223 patients with Paget's disease, and their K-rays have been analysed for the extent and distribution of skeletal involvement. 90' show disease in the pelvis, lumbar spine and upper ends of the femora, and 31c6 have monostotic disease. Males arc more frequently affected than females. Prevalence and extent of the disease rise with age. Greater involvement of the lower limb than the upper limb, a right sided tendency in the limb girdles, and preferential involvement of certain regions of the spine all suggest that bone stress may be significant in the pathogenesis. Examination of the request cards, X-ray reports, and clinical response to the report, reveals that 3496 of patients had symptons recorded which -ere referable to their bone disease. The type of initial radiological examination appears to be of little relevance to the prevalence of the bc:1e disease. The onset of symptoms uay occasionally be in tile third decade but is rencrail.y Inter. The Main synp I to ysinns, :nd caala `. cation are pain, deformity, fracture, evidence of malignancy, and (rarely) spinal cord compression. The results of this survey suggest that Paget's disease of bone may be due to absorption of an external agent, and that the bone changes arc related to bone stress.

This record has no associated files available for download.

More information

Published date: 1977

Identifiers

Local EPrints ID: 458824
URI: http://eprints.soton.ac.uk/id/eprint/458824
PURE UUID: 1b60c238-4cdb-4fdb-94c0-068bdd17f287

Catalogue record

Date deposited: 04 Jul 2022 16:56
Last modified: 04 Jul 2022 16:56

Export record

Contributors

Author: Peter Brett Guyer

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×