Mead, Keith Thomas (1982) Some aspects of sulphur in organic synthesis. University of Southampton, Doctoral Thesis.
Abstract
The development of novel synthetic methods in organic chemistry is important for it allows the construction of complex molecules by new routes. Studies were made on the anion derived from 3-dimethylamino-lphenylthioprop-l-ene with the view to developing a new a,8-unsaturated acyl anion equivalent. A new route to substituted 1,3-bis(phenylthio) alk-l-enes was discovered and is described in Chapter One. Chapter Two describes new approaches to cyclopent-2-enones. 1-Phenylthio-2-(phenylthiomethyl)cyclopent-l-ene was prepared and the anion of this reacted with a number of electrophiles. Alkylated products were hydrolysed with mercuric chloride providing a cyclopentanone-2methylidene anion equivalent and, potentially, a new general route to cyclopent-2-enones.Pyrindicin, a fungal metabolite of biological interest, is the topic of Chapter Three. The attempted synthesis of this alkaloid by several routes was not successful.
This record has no associated files available for download.
More information
Identifiers
Catalogue record
Export record
Contributors
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.