Computer simulation of trachoma
Computer simulation of trachoma
Trachoma is one of the world's major causes of preventable blindness. It is restricted to poor socioeconomic areas and is estimated to affect some 300-500 million people world wide with some 7 million blind as a direct consequence. Considerable money, time and effort are being invested with the objective of combating trachoma. There are several approaches being implemented, including vaccine development and antibiotic treatment, although the actual effects that these strategies will have is not known. This thesis describes the development of a trachoma simulation model based on specially collected data from a West African village with hyper-endemic trachoma - Jali, in The Gambia. This model can simulate the effects of proposed socioeconomic improvements, vaccinations or chemotherapy on various clinical states of trachoma, including conjunctival scarring and severe visual loss. Thus, the effects of proposed campaigns and strategies can be flexibly evaluated before implementation.
University of Southampton
Hawkins, James David
4fa55c5a-9e62-4338-b773-2bb1c8f04a2d
1989
Hawkins, James David
4fa55c5a-9e62-4338-b773-2bb1c8f04a2d
Hawkins, James David
(1989)
Computer simulation of trachoma.
University of Southampton, Doctoral Thesis.
Record type:
Thesis
(Doctoral)
Abstract
Trachoma is one of the world's major causes of preventable blindness. It is restricted to poor socioeconomic areas and is estimated to affect some 300-500 million people world wide with some 7 million blind as a direct consequence. Considerable money, time and effort are being invested with the objective of combating trachoma. There are several approaches being implemented, including vaccine development and antibiotic treatment, although the actual effects that these strategies will have is not known. This thesis describes the development of a trachoma simulation model based on specially collected data from a West African village with hyper-endemic trachoma - Jali, in The Gambia. This model can simulate the effects of proposed socioeconomic improvements, vaccinations or chemotherapy on various clinical states of trachoma, including conjunctival scarring and severe visual loss. Thus, the effects of proposed campaigns and strategies can be flexibly evaluated before implementation.
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Published date: 1989
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Local EPrints ID: 461820
URI: http://eprints.soton.ac.uk/id/eprint/461820
PURE UUID: cd58d4d3-4f47-4a70-9e7d-3c2105ce09f7
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Date deposited: 04 Jul 2022 18:56
Last modified: 23 Jul 2022 00:34
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Author:
James David Hawkins
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