Models to evaluate schemes for an early detection of breast cancer
Models to evaluate schemes for an early detection of breast cancer
Prevention of cancer in general, and breast cancer in particular is not possible at present. In the absence of prevention an early detection through screening is sometimes an attractive course of action. Evidence that sreening for an early detection of breast cancer may be worthwhile has been accumulating since an early study in New York (the HIP study, 1963). The decision to screen a community has a number of serious implications. Having established that early detection is beneficial, mathematical and simulation models are needed to assess and evaluate different screening programs in terms of the stage of disease at detection and the cost of the tests every woman receives. Models are developed to assist public policymakers in assessing screening schemes for an early detection of breast cancer. The impact of changes in the combination of up to three screening procedures used, the frequency with which each procedure is used, and the period of time during which screening is offered, can be investigated. Policies are evaluated in terms of progress of disease at detection, expected cost of the tests, the probability of detection by screening, and the number of false positives produced. The model is implemented on an IBM-PC computer. The program offers an interactive and user-friendly environment so that different schemes can be tried easily. (D76677)
University of Southampton
Ouinten, Youcef
748e30e8-f961-44a9-b497-13525c0dbfa4
1988
Ouinten, Youcef
748e30e8-f961-44a9-b497-13525c0dbfa4
Ouinten, Youcef
(1988)
Models to evaluate schemes for an early detection of breast cancer.
University of Southampton, Doctoral Thesis.
Record type:
Thesis
(Doctoral)
Abstract
Prevention of cancer in general, and breast cancer in particular is not possible at present. In the absence of prevention an early detection through screening is sometimes an attractive course of action. Evidence that sreening for an early detection of breast cancer may be worthwhile has been accumulating since an early study in New York (the HIP study, 1963). The decision to screen a community has a number of serious implications. Having established that early detection is beneficial, mathematical and simulation models are needed to assess and evaluate different screening programs in terms of the stage of disease at detection and the cost of the tests every woman receives. Models are developed to assist public policymakers in assessing screening schemes for an early detection of breast cancer. The impact of changes in the combination of up to three screening procedures used, the frequency with which each procedure is used, and the period of time during which screening is offered, can be investigated. Policies are evaluated in terms of progress of disease at detection, expected cost of the tests, the probability of detection by screening, and the number of false positives produced. The model is implemented on an IBM-PC computer. The program offers an interactive and user-friendly environment so that different schemes can be tried easily. (D76677)
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Published date: 1988
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Local EPrints ID: 461821
URI: http://eprints.soton.ac.uk/id/eprint/461821
PURE UUID: 7eb6a174-2d57-47e1-9d3c-3053225d0155
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Date deposited: 04 Jul 2022 18:56
Last modified: 23 Jul 2022 00:34
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Author:
Youcef Ouinten
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