A non-invasive study of cutaneous perfusion around leg ulcers
A non-invasive study of cutaneous perfusion around leg ulcers
One of the problems which commonly affect the elderly is ulceration of the legs. The nature and extent of this problem suggest the need for investigations which could help in the clinical management of leg ulcers. An appraisal of the established investigative methods showed the need for alternative techniques to study the cutaneous perfusion around ulcers. Two different techniques, one based on the optical diffusion of light and the other on Polarography, were selected and an optical probe was designed and developed. Individual and combined validation studies on the probes were conducted and a protocol for investigating leg ulcers using non-invasive methods was designed. An increase in tissue oxygen tension was associated with favourable response in a small number of venous ulcers. The methods of measuring blood pulse volume and tissue oxygen tension were found to be related to each other. The measurement of tissue oxygen tension was also found to be significantly related to the observed outcome. The detection of blood pulse volume was found to have a non-significant bearing on the outcome. The studies showed the value of the techniques used for the different measurements as well as the designed protocol. (D82757)
University of Southampton
1987
Mani, Rajgopal
(1987)
A non-invasive study of cutaneous perfusion around leg ulcers.
University of Southampton, Doctoral Thesis.
Record type:
Thesis
(Doctoral)
Abstract
One of the problems which commonly affect the elderly is ulceration of the legs. The nature and extent of this problem suggest the need for investigations which could help in the clinical management of leg ulcers. An appraisal of the established investigative methods showed the need for alternative techniques to study the cutaneous perfusion around ulcers. Two different techniques, one based on the optical diffusion of light and the other on Polarography, were selected and an optical probe was designed and developed. Individual and combined validation studies on the probes were conducted and a protocol for investigating leg ulcers using non-invasive methods was designed. An increase in tissue oxygen tension was associated with favourable response in a small number of venous ulcers. The methods of measuring blood pulse volume and tissue oxygen tension were found to be related to each other. The measurement of tissue oxygen tension was also found to be significantly related to the observed outcome. The detection of blood pulse volume was found to have a non-significant bearing on the outcome. The studies showed the value of the techniques used for the different measurements as well as the designed protocol. (D82757)
This record has no associated files available for download.
More information
Published date: 1987
Identifiers
Local EPrints ID: 461948
URI: http://eprints.soton.ac.uk/id/eprint/461948
PURE UUID: ac1c6fa7-5223-4632-a246-1775b1ccd927
Catalogue record
Date deposited: 04 Jul 2022 18:59
Last modified: 04 Jul 2022 18:59
Export record
Contributors
Author:
Rajgopal Mani
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics