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On dyspnoea in advanced cancer

On dyspnoea in advanced cancer
On dyspnoea in advanced cancer

The literature on dyspnoea in advanced cancer is reviewed. In a study of 968 patients, dyspnoea was shown to be common and commonly severe. Survival was inversely proportional to severity and prevalence. Established methods of measuring dyspnoea - visual analogue scales (VAS) and word and numeric scales were tested. A new measure of dyspnoea, the Dyspnoea Assessment Questionnaire (DAQ) was developed incorporating qualitative as well as quantitative aspects of dyspnoea. It correlated well with the VAS. Dyspnoea was less well controlled than pain. Another new measure, the Dyspnoea Exertion Score (DES) did not correlate with VAS scores.

Measurement of psychological status by the Crown-Crisp Experiential Index (CCEI) showed raised scores for anxiety, obsessionality and depression for terminal cancer patients. In dyspnoeic patients, only anxiety levels were higher than in the non-dyspnoeic. Lung and pleural tumours, smoking and the hyperventilation syndrome (HVS) were risk factors for dyspnoea. The Hyperventilation Provocation Test (HVPT) was used to diagnose HVS. CCEI anxiety scores were higher in HVS than in either non-HVS or dyspnoeic patients. HVS was diagnosed in 1 in 5 patients tested.

In conclusion: dyspnoea is a major problem in advanced cancer; a new method of measuring it was developed; HVS is a common cause.

University of Southampton
Heyse-Moore, Louis Henry
efe8a643-f0dd-4801-afb9-b7f8a6d8bfdf
Heyse-Moore, Louis Henry
efe8a643-f0dd-4801-afb9-b7f8a6d8bfdf

Heyse-Moore, Louis Henry (1993) On dyspnoea in advanced cancer. University of Southampton, Doctoral Thesis.

Record type: Thesis (Doctoral)

Abstract

The literature on dyspnoea in advanced cancer is reviewed. In a study of 968 patients, dyspnoea was shown to be common and commonly severe. Survival was inversely proportional to severity and prevalence. Established methods of measuring dyspnoea - visual analogue scales (VAS) and word and numeric scales were tested. A new measure of dyspnoea, the Dyspnoea Assessment Questionnaire (DAQ) was developed incorporating qualitative as well as quantitative aspects of dyspnoea. It correlated well with the VAS. Dyspnoea was less well controlled than pain. Another new measure, the Dyspnoea Exertion Score (DES) did not correlate with VAS scores.

Measurement of psychological status by the Crown-Crisp Experiential Index (CCEI) showed raised scores for anxiety, obsessionality and depression for terminal cancer patients. In dyspnoeic patients, only anxiety levels were higher than in the non-dyspnoeic. Lung and pleural tumours, smoking and the hyperventilation syndrome (HVS) were risk factors for dyspnoea. The Hyperventilation Provocation Test (HVPT) was used to diagnose HVS. CCEI anxiety scores were higher in HVS than in either non-HVS or dyspnoeic patients. HVS was diagnosed in 1 in 5 patients tested.

In conclusion: dyspnoea is a major problem in advanced cancer; a new method of measuring it was developed; HVS is a common cause.

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Published date: 1993

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Local EPrints ID: 462375
URI: http://eprints.soton.ac.uk/id/eprint/462375
PURE UUID: 9556bf56-acde-4535-9fc2-654ad645a9ef

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Date deposited: 04 Jul 2022 19:06
Last modified: 16 Mar 2024 18:55

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Author: Louis Henry Heyse-Moore

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