Harvey, Darren Keith (1998) Design of a Compton Camera for nuclear medicine. University of Southampton, Doctoral Thesis.
Abstract
The Compton Camera system shows potential for improving the efficiency of γ-ray imaging. This would be especially beneficial in the field of nuclear medicine where lower doses or imaging times could be used. The prime difficulty encountered with the Compton Camera is the complex image processing. The object of this work is to design an image processing technique suitable for the Compton Camera, a secondary objective is to design a physical detector arrangement optimised for the image processing; the method by which this may be achieved is explained.
A number of image processing techniques have been investigated and compared. A completely new image reconstruction technique, Multi Photon Back Projection, is developed. A novel implementation of the Maximum Likelihood technique and an extension to a popular Maximum Entropy algorithm, to deal with low detector counts, are also presented.
It is concluded that the large data sets generated by the Compton Camera will take a prohibitive amount of time to reconstruct by the more complex reconstruction algorithms. In addition, the time taken to perform the simplest operation on the Compton Camera data will prevent its use in nuclear medicine until there is a significant increase in computational power.
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