Nutritional aspects of bone health and muscle performance in the elderly in the UK
Nutritional aspects of bone health and muscle performance in the elderly in the UK
This study tests the hypothesis that a diet, which complies with current healthy dietary guidelines, is associated with lower plasma alkaline phosphatase (ALP) and stronger handgrip strength as markers of bone health and muscle performance in older people. The study also examines whether men, and those with optimal early nutrition will benefit more from a healthy diet than women and those from a less than optimal early environment. This is the first study to examine the effect of a healthy dietary pattern and to explore its interactions with sex and body size measurements on bone health and muscle performance in the elderly.
The secondary analyses undertaken in this study are based on the data of the National Diet and Nutrition Survey (NDNS) conducted on a UK nationally-representative sample of 1687 men and women aged 65 years and over. Principal component analysis (PCA) was used to summarise dietary patterns, by which seven statistically independent eating patterns were generated.
The healthy dietary pattern identified by PCA characterised by a high intake of vegetables, fruits, cereals, fish and other seafood, showed that strongest negative (beneficial) association with ALP (r = -0.17, p<0.001) and the strongest positive association with hand-grip strength (r = 0.20, p<0.001). Multiple regression analysis controlling for energy intake, a number of confounders and various nutrients, identified the healthy diet as the strongest predictor for serum ALP and handgrip strength in elderly men and women, separately. Subjects in the highest fourth of the healthy diet in comparison to the lowest, were less likely to have high levels of plasma ALP (OR = 0.4, 95% CI, 0.3 - 0.6) after adjustment for known confounders. Healthy diet was of the most benefit for heaviest and tallest men but not heavier and taller women. For those within the shortest and thinnest group, the association between healthy diet and ALP did not reach statistical significance.
University of Southampton
Safarian, Mohammad
01e6a7c5-10df-4dfb-a221-3bf760d07d73
2003
Safarian, Mohammad
01e6a7c5-10df-4dfb-a221-3bf760d07d73
Safarian, Mohammad
(2003)
Nutritional aspects of bone health and muscle performance in the elderly in the UK.
University of Southampton, Doctoral Thesis.
Record type:
Thesis
(Doctoral)
Abstract
This study tests the hypothesis that a diet, which complies with current healthy dietary guidelines, is associated with lower plasma alkaline phosphatase (ALP) and stronger handgrip strength as markers of bone health and muscle performance in older people. The study also examines whether men, and those with optimal early nutrition will benefit more from a healthy diet than women and those from a less than optimal early environment. This is the first study to examine the effect of a healthy dietary pattern and to explore its interactions with sex and body size measurements on bone health and muscle performance in the elderly.
The secondary analyses undertaken in this study are based on the data of the National Diet and Nutrition Survey (NDNS) conducted on a UK nationally-representative sample of 1687 men and women aged 65 years and over. Principal component analysis (PCA) was used to summarise dietary patterns, by which seven statistically independent eating patterns were generated.
The healthy dietary pattern identified by PCA characterised by a high intake of vegetables, fruits, cereals, fish and other seafood, showed that strongest negative (beneficial) association with ALP (r = -0.17, p<0.001) and the strongest positive association with hand-grip strength (r = 0.20, p<0.001). Multiple regression analysis controlling for energy intake, a number of confounders and various nutrients, identified the healthy diet as the strongest predictor for serum ALP and handgrip strength in elderly men and women, separately. Subjects in the highest fourth of the healthy diet in comparison to the lowest, were less likely to have high levels of plasma ALP (OR = 0.4, 95% CI, 0.3 - 0.6) after adjustment for known confounders. Healthy diet was of the most benefit for heaviest and tallest men but not heavier and taller women. For those within the shortest and thinnest group, the association between healthy diet and ALP did not reach statistical significance.
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Published date: 2003
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Local EPrints ID: 465138
URI: http://eprints.soton.ac.uk/id/eprint/465138
PURE UUID: ad442c46-860c-471f-9095-71933d2d2771
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Date deposited: 05 Jul 2022 00:25
Last modified: 16 Mar 2024 19:58
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Author:
Mohammad Safarian
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