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Sulfonyl chloride resins and associated supported reagents

Sulfonyl chloride resins and associated supported reagents
Sulfonyl chloride resins and associated supported reagents

The use of sulfonyl chloride resins in organic synthesis and as precursors for supported reagents has been well documented, and has highlighted shortcomings in using currently available commercial resins.  The aim of this study has been to investigate the synthesis of novel sulfonyl chloride and sulfonyl containing resins and their uses in synthesis and for supported reagents.

A number of supported reagents have been identified as useful targets.  Solid-supported reagents can remove any associated hazards involved in using their solution-phase counterparts.  Examples include a supported version of sulfonyl azide, used in diazo-transfer reactions and supported O-sulfonyl hydroxylamines as an alternative to reagents such as MSH (Mesitylenesulfonyl hydroxylamine).

University of Southampton
Hughes, Robert Michael
91e3ab38-6c4d-44f1-8050-0c538610ca93
Hughes, Robert Michael
91e3ab38-6c4d-44f1-8050-0c538610ca93

Hughes, Robert Michael (2004) Sulfonyl chloride resins and associated supported reagents. University of Southampton, Doctoral Thesis.

Record type: Thesis (Doctoral)

Abstract

The use of sulfonyl chloride resins in organic synthesis and as precursors for supported reagents has been well documented, and has highlighted shortcomings in using currently available commercial resins.  The aim of this study has been to investigate the synthesis of novel sulfonyl chloride and sulfonyl containing resins and their uses in synthesis and for supported reagents.

A number of supported reagents have been identified as useful targets.  Solid-supported reagents can remove any associated hazards involved in using their solution-phase counterparts.  Examples include a supported version of sulfonyl azide, used in diazo-transfer reactions and supported O-sulfonyl hydroxylamines as an alternative to reagents such as MSH (Mesitylenesulfonyl hydroxylamine).

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Published date: 2004

Identifiers

Local EPrints ID: 465159
URI: http://eprints.soton.ac.uk/id/eprint/465159
PURE UUID: e1446ba6-213e-4a36-8da6-9929867a8c20

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Date deposited: 05 Jul 2022 00:26
Last modified: 16 Mar 2024 19:59

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Contributors

Author: Robert Michael Hughes

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