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The synthesis of novel chiral transition metal complexes

The synthesis of novel chiral transition metal complexes
The synthesis of novel chiral transition metal complexes

The synthesis of a variety of novel chiral annulated and C2-symmteric cyclopentadienyl ligands and the formation of a novel titanocene complex is described.  Chapter 1 provides an introduction to the research, outlining the methodology and stating the aims of the project.  A literature review of chiral annulated Cyclopentadienyl ligands and the use of Group IV metallocenes as chiral catalysts is in asymmetric synthesis is discussed.  Chapter two deals with the development of a chiral double Michael addition reaction, via the synthesis of 4-substituted chiral cyclopentenones, the products of which are intended for use as chiral Cyclopentadienyl ligands.  Chapter three introduces a novel C2-symmetric ligand design, and the synthesis thereof, whilst chapter 4 presents the complexation of the novel C2-symmetric ligand to form a titanocene complex.  Experimental details are given in chapter 5.

University of Southampton
Dossett, David Michael
5abb31bb-7166-477a-bc66-8dabcca07600
Dossett, David Michael
5abb31bb-7166-477a-bc66-8dabcca07600

Dossett, David Michael (2003) The synthesis of novel chiral transition metal complexes. University of Southampton, Doctoral Thesis.

Record type: Thesis (Doctoral)

Abstract

The synthesis of a variety of novel chiral annulated and C2-symmteric cyclopentadienyl ligands and the formation of a novel titanocene complex is described.  Chapter 1 provides an introduction to the research, outlining the methodology and stating the aims of the project.  A literature review of chiral annulated Cyclopentadienyl ligands and the use of Group IV metallocenes as chiral catalysts is in asymmetric synthesis is discussed.  Chapter two deals with the development of a chiral double Michael addition reaction, via the synthesis of 4-substituted chiral cyclopentenones, the products of which are intended for use as chiral Cyclopentadienyl ligands.  Chapter three introduces a novel C2-symmetric ligand design, and the synthesis thereof, whilst chapter 4 presents the complexation of the novel C2-symmetric ligand to form a titanocene complex.  Experimental details are given in chapter 5.

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Published date: 2003

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Local EPrints ID: 465250
URI: http://eprints.soton.ac.uk/id/eprint/465250
PURE UUID: 5f00a98d-2588-41e1-a3af-307095bb2895

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Date deposited: 05 Jul 2022 00:31
Last modified: 16 Mar 2024 20:03

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Author: David Michael Dossett

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