Palladium-catalysed synthesis of amidines and imidates
Palladium-catalysed synthesis of amidines and imidates
A novel palladium-catalysed three-component synthesis of alkenyl amidines and imidates from alkenyl bromides, isonitriles and amines or alcohols was developed. The amidine synthesis utilised CS2CO3 as the base and was limited to tert-buiyl isonitrile. In the imidate synthesis NaO'Bu was the base and different isonitriles were successfully utilised. The stereochemistry of the group in alkenyl bromide was retained in the product. The stereochemistry of the imine double bond in two of the amidines was shown to be the thermodynamically more stable (^-isomer by X- ray crystallography.
University of Southampton
Tetala, Kali Kishore Reddy
4c628ebc-0212-4ba4-821f-aa08ccdbe66a
2004
Tetala, Kali Kishore Reddy
4c628ebc-0212-4ba4-821f-aa08ccdbe66a
Tetala, Kali Kishore Reddy
(2004)
Palladium-catalysed synthesis of amidines and imidates.
University of Southampton, Doctoral Thesis.
Record type:
Thesis
(Doctoral)
Abstract
A novel palladium-catalysed three-component synthesis of alkenyl amidines and imidates from alkenyl bromides, isonitriles and amines or alcohols was developed. The amidine synthesis utilised CS2CO3 as the base and was limited to tert-buiyl isonitrile. In the imidate synthesis NaO'Bu was the base and different isonitriles were successfully utilised. The stereochemistry of the group in alkenyl bromide was retained in the product. The stereochemistry of the imine double bond in two of the amidines was shown to be the thermodynamically more stable (^-isomer by X- ray crystallography.
Text
942544.pdf
- Version of Record
More information
Published date: 2004
Identifiers
Local EPrints ID: 465330
URI: http://eprints.soton.ac.uk/id/eprint/465330
PURE UUID: 11f42c29-bb5b-4285-9516-c53bdfb6c0d3
Catalogue record
Date deposited: 05 Jul 2022 00:38
Last modified: 16 Mar 2024 20:06
Export record
Contributors
Author:
Kali Kishore Reddy Tetala
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics