Prevalence of 'novel' food allergens worldwide:: A systematic review
Prevalence of 'novel' food allergens worldwide:: A systematic review
Rationale: Systematically identifying and reviewing population-based studies reporting the prevalence of food allergy enables geographical variations to be described and helps to identify the prevalence of novel food allergens. Such information can inform evidence-based policy and practice at a national and international level, while also identifying gaps in the current evidence base.
Objective: To investigate the prevalence, by age, of food allergy to celery, lupin, mustard and sesame in different regions of the world. This systematic review formed part of a wider investigation on the prevalence of a range of allergen
Methodology: Systematic searches were conducted using two databases; Web of Science and Pubmed. Grey literature was identified by searching conference proceedings and by consultation with experts in the field. Search results were managed using reference management software. Titles and abstracts, and the full-text of potentially eligible articles were screened for inclusion by the review authors according to the following criteria:
Relevant data was extracted from all included studies, and the quality of included studies assessed. All allergens were initially included, however for the purpose of this study only data relevant to celery, lupin, mustard and sesame are presented
Results:
CELERY: There were four studies which reported prevalence data for celery in Europe as well as the United States and Australia
LUPIN: No studies could be found which reported the prevalence of lupin allergy
MUSTARD: There were two studies which reported prevalence data for mustard in Europe and the United States and Australia
SESAME: There were 13 studies which reported prevalence date for sesame in Europe as well as Canada, Australia and the United States
Conclusions: There is surprisingly little data available on the prevalence of these novel food allergens despite the fact that they appear in the top 14 food allergens listed by the EU. Furthermore, the gold-standard of diagnosis, food challenges, were only adopted in one study which looked at sesame allergy in children. Further studies which confirm allergy based on food challenges are needed to understand the true effect these allergens have on the general population. Since the present review was conducted, we are aware that DBPCFC data for celery allergy has emerged from the EuroPrevall project which reports that 41 out of 64 patients (64.1%) who self-reported an adverse reaction to celery experienced a positive reaction when challenged.
Moonsinghe, Harriet
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Sally, Kilburn
8fa10f77-f698-4e17-82e1-647b0408c62d
Mackenzie, Heather
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Venter, Carina
ec22e542-cc42-4428-b86f-b562f6a5d91a
Lee, Kellyn
6c8c3a3e-f987-4ca0-b1a6-466afeeb399c
Dean, Taraneh
1bb6a824-55c0-484a-a3f9-3f4ea60912fc
9 October 2014
Moonsinghe, Harriet
f51cc806-0964-498e-b073-bbaf375f49e3
Sally, Kilburn
8fa10f77-f698-4e17-82e1-647b0408c62d
Mackenzie, Heather
e1e524b1-b525-4da4-a7d3-d0bb359f4680
Venter, Carina
ec22e542-cc42-4428-b86f-b562f6a5d91a
Lee, Kellyn
6c8c3a3e-f987-4ca0-b1a6-466afeeb399c
Dean, Taraneh
1bb6a824-55c0-484a-a3f9-3f4ea60912fc
Moonsinghe, Harriet, Sally, Kilburn, Mackenzie, Heather, Venter, Carina, Lee, Kellyn and Dean, Taraneh
(2014)
Prevalence of 'novel' food allergens worldwide:: A systematic review.
Record type:
Conference or Workshop Item
(Poster)
Abstract
Rationale: Systematically identifying and reviewing population-based studies reporting the prevalence of food allergy enables geographical variations to be described and helps to identify the prevalence of novel food allergens. Such information can inform evidence-based policy and practice at a national and international level, while also identifying gaps in the current evidence base.
Objective: To investigate the prevalence, by age, of food allergy to celery, lupin, mustard and sesame in different regions of the world. This systematic review formed part of a wider investigation on the prevalence of a range of allergen
Methodology: Systematic searches were conducted using two databases; Web of Science and Pubmed. Grey literature was identified by searching conference proceedings and by consultation with experts in the field. Search results were managed using reference management software. Titles and abstracts, and the full-text of potentially eligible articles were screened for inclusion by the review authors according to the following criteria:
Relevant data was extracted from all included studies, and the quality of included studies assessed. All allergens were initially included, however for the purpose of this study only data relevant to celery, lupin, mustard and sesame are presented
Results:
CELERY: There were four studies which reported prevalence data for celery in Europe as well as the United States and Australia
LUPIN: No studies could be found which reported the prevalence of lupin allergy
MUSTARD: There were two studies which reported prevalence data for mustard in Europe and the United States and Australia
SESAME: There were 13 studies which reported prevalence date for sesame in Europe as well as Canada, Australia and the United States
Conclusions: There is surprisingly little data available on the prevalence of these novel food allergens despite the fact that they appear in the top 14 food allergens listed by the EU. Furthermore, the gold-standard of diagnosis, food challenges, were only adopted in one study which looked at sesame allergy in children. Further studies which confirm allergy based on food challenges are needed to understand the true effect these allergens have on the general population. Since the present review was conducted, we are aware that DBPCFC data for celery allergy has emerged from the EuroPrevall project which reports that 41 out of 64 patients (64.1%) who self-reported an adverse reaction to celery experienced a positive reaction when challenged.
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More information
Published date: 9 October 2014
Identifiers
Local EPrints ID: 467470
URI: http://eprints.soton.ac.uk/id/eprint/467470
PURE UUID: c11980f6-f8a2-4883-af4d-2aec09b7ef44
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Date deposited: 08 Jul 2022 16:53
Last modified: 17 Mar 2024 04:00
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Contributors
Author:
Harriet Moonsinghe
Author:
Kilburn Sally
Author:
Heather Mackenzie
Author:
Carina Venter
Author:
Taraneh Dean
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