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The direct and indirect effects of COVID-19 on Acute Coronary Syndromes

The direct and indirect effects of COVID-19 on Acute Coronary Syndromes
The direct and indirect effects of COVID-19 on Acute Coronary Syndromes
Highlights: The COVID-19 pandemic has resulted in wide-ranging direct and indirect consequences for patients with ACS.•A sudden, unexpected decline in hospitalizations for ACS and an increase in out-of-hospital deaths coincided with the onset of the COVID-19 pandemic.•ACS in patients with COVID-19 is associated with excess rates of adverse events, particularly when medical intervention is delayed.•During the COVID-19 pandemic, many patients with ACS have been required to undergo alternative diagnostic and therapeutic strategies due to reorganization of health care resources.•Studies to further elucidate the complex relationship between SARS-CoV-2 infection and myocardial injury or infarction are required.
Acute coronary syndrome, COVID-19, Non–ST-elevation myocardial infarction, ST-elevation myocardial infarction
0733-8651
309-320
Kite, Thomas A.
6eaf2e82-e7f5-4239-8aa3-0a77646a49ba
Pallikadavath, Susil
a9e5a9d8-a414-41f9-8893-9af9226717b5
Gale, Chris P.
96b5706c-fd86-4b41-9568-3d917ef2c805
Curzen, Nick
70f3ea49-51b1-418f-8e56-8210aef1abf4
Ladwiniec, Andrew
ef6781f6-015a-4bfa-96a4-b3910e4ddc15
Kite, Thomas A.
6eaf2e82-e7f5-4239-8aa3-0a77646a49ba
Pallikadavath, Susil
a9e5a9d8-a414-41f9-8893-9af9226717b5
Gale, Chris P.
96b5706c-fd86-4b41-9568-3d917ef2c805
Curzen, Nick
70f3ea49-51b1-418f-8e56-8210aef1abf4
Ladwiniec, Andrew
ef6781f6-015a-4bfa-96a4-b3910e4ddc15

Kite, Thomas A., Pallikadavath, Susil, Gale, Chris P., Curzen, Nick and Ladwiniec, Andrew (2022) The direct and indirect effects of COVID-19 on Acute Coronary Syndromes. Cardiology Clinics, 40 (3), 309-320. (doi:10.1016/j.ccl.2022.03.002).

Record type: Article

Abstract

Highlights: The COVID-19 pandemic has resulted in wide-ranging direct and indirect consequences for patients with ACS.•A sudden, unexpected decline in hospitalizations for ACS and an increase in out-of-hospital deaths coincided with the onset of the COVID-19 pandemic.•ACS in patients with COVID-19 is associated with excess rates of adverse events, particularly when medical intervention is delayed.•During the COVID-19 pandemic, many patients with ACS have been required to undergo alternative diagnostic and therapeutic strategies due to reorganization of health care resources.•Studies to further elucidate the complex relationship between SARS-CoV-2 infection and myocardial injury or infarction are required.

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More information

e-pub ahead of print date: 23 March 2022
Published date: 1 August 2022
Additional Information: Funding Information: C.P. Gale reports personal fees from AstraZeneca, Amgen, Bayer, Boehringer-Ingelheim, Daiichi Sankyo, Vifor Pharma, Menarini, Wondr Medical, Raisio Group, and Oxford University Press; grants from BMS, Abbott, British Heart Foundation , National Institute for Health Research , Horizon 2020 , and ESC , outside the submitted work. N. Curzen reports unrestricted research grants from Boston Scientific , HeartFlow , and Beckman Coulter , and speaker/consultancy fees from Boston, Abbott, and HeartFlow outside the submitted work. The remaining authors have no conflicts of interest to declare. Funding Information: C.P. Gale reports personal fees from AstraZeneca, Amgen, Bayer, Boehringer-Ingelheim, Daiichi Sankyo, Vifor Pharma, Menarini, Wondr Medical, Raisio Group, and Oxford University Press; grants from BMS, Abbott, British Heart Foundation, National Institute for Health Research, Horizon 2020, and ESC, outside the submitted work. N. Curzen reports unrestricted research grants from Boston Scientific, HeartFlow, and Beckman Coulter, and speaker/consultancy fees from Boston, Abbott, and HeartFlow outside the submitted work. The remaining authors have no conflicts of interest to declare.
Keywords: Acute coronary syndrome, COVID-19, Non–ST-elevation myocardial infarction, ST-elevation myocardial infarction

Identifiers

Local EPrints ID: 467867
URI: http://eprints.soton.ac.uk/id/eprint/467867
ISSN: 0733-8651
PURE UUID: 2e2c031e-871a-46af-8637-86d0dd1956b4
ORCID for Nick Curzen: ORCID iD orcid.org/0000-0001-9651-7829

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Date deposited: 22 Jul 2022 16:39
Last modified: 17 Mar 2024 03:02

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Contributors

Author: Thomas A. Kite
Author: Susil Pallikadavath
Author: Chris P. Gale
Author: Nick Curzen ORCID iD
Author: Andrew Ladwiniec

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