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Feasibility study for the use of Ce3+-doped optical fibres in radiotherapy

Feasibility study for the use of Ce3+-doped optical fibres in radiotherapy
Feasibility study for the use of Ce3+-doped optical fibres in radiotherapy
A feasibility study for the use of a Ce-doped optical fibre as a radioluminescent dosimeter in radiotherapy was carried out. The prototype showed a satisfactory reproducibility (1.7%) and a good linearity over a clinically relevant dose range (from few cGy to approximately 10 Gy). Moreover, the device enabled a reliable evaluation of the absorbed dose, independently of the dose rate and of the orientation of the incoming radiation. A slight energy dependence of the response was observed when the system was irradiated with electron beams of different energies. The results indicate that the employment of this new system might be very promising both for quality control measurements and "in vivo" dosimetry. Some improvements are nevertheless still required in order to allow a real-time evaluation of the Cherenkov radiation produced by the irradiated portion of the passive optical fibre, which influences some of the dosimetric properties of the system.
radiotherapy dosimetry, optical fibre, radioluminescence
0168-9002
449-455
Mones, E.
e79a1204-ab2d-4188-a206-ca6ce3b6a65c
Veronese, I.
83c2ead7-185a-471f-8c10-deb741dce585
Moretti, F.
03e06974-311e-4011-b5ca-7b5ce2635aa9
Fasoli, M.
4cd1a128-6f54-4f5b-bb88-6c129df535b6
Loi, G.
e93b7f3b-9d4d-4a8b-afa0-fe0c3331dfbd
Negri, E.
26b2220d-513f-444d-a8f9-aaf2055c12c6
Brambilla, M.
161bd164-d31c-4eda-b811-985e92eb8c31
Chiodini, N.
d516f93d-7d8e-4033-b1be-b33ad58bf4f6
Brambilla, G.
815d9712-62c7-47d1-8860-9451a363a6c8
Vedda, A.
f048b76f-ff98-4909-b82e-b383a38a2bcf
Mones, E.
e79a1204-ab2d-4188-a206-ca6ce3b6a65c
Veronese, I.
83c2ead7-185a-471f-8c10-deb741dce585
Moretti, F.
03e06974-311e-4011-b5ca-7b5ce2635aa9
Fasoli, M.
4cd1a128-6f54-4f5b-bb88-6c129df535b6
Loi, G.
e93b7f3b-9d4d-4a8b-afa0-fe0c3331dfbd
Negri, E.
26b2220d-513f-444d-a8f9-aaf2055c12c6
Brambilla, M.
161bd164-d31c-4eda-b811-985e92eb8c31
Chiodini, N.
d516f93d-7d8e-4033-b1be-b33ad58bf4f6
Brambilla, G.
815d9712-62c7-47d1-8860-9451a363a6c8
Vedda, A.
f048b76f-ff98-4909-b82e-b383a38a2bcf

Mones, E., Veronese, I., Moretti, F., Fasoli, M., Loi, G., Negri, E., Brambilla, M., Chiodini, N., Brambilla, G. and Vedda, A. (2006) Feasibility study for the use of Ce3+-doped optical fibres in radiotherapy. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 562 (1), 449-455. (doi:10.1016/j.nima.2006.02.003).

Record type: Article

Abstract

A feasibility study for the use of a Ce-doped optical fibre as a radioluminescent dosimeter in radiotherapy was carried out. The prototype showed a satisfactory reproducibility (1.7%) and a good linearity over a clinically relevant dose range (from few cGy to approximately 10 Gy). Moreover, the device enabled a reliable evaluation of the absorbed dose, independently of the dose rate and of the orientation of the incoming radiation. A slight energy dependence of the response was observed when the system was irradiated with electron beams of different energies. The results indicate that the employment of this new system might be very promising both for quality control measurements and "in vivo" dosimetry. Some improvements are nevertheless still required in order to allow a real-time evaluation of the Cherenkov radiation produced by the irradiated portion of the passive optical fibre, which influences some of the dosimetric properties of the system.

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More information

e-pub ahead of print date: June 2006
Keywords: radiotherapy dosimetry, optical fibre, radioluminescence
Organisations: Optoelectronics Research Centre

Identifiers

Local EPrints ID: 46879
URI: http://eprints.soton.ac.uk/id/eprint/46879
ISSN: 0168-9002
PURE UUID: 0b76ff22-ae16-4a27-8f0a-14e56782487a
ORCID for G. Brambilla: ORCID iD orcid.org/0000-0002-5730-0499

Catalogue record

Date deposited: 23 Jul 2007
Last modified: 02 Apr 2022 01:37

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Contributors

Author: E. Mones
Author: I. Veronese
Author: F. Moretti
Author: M. Fasoli
Author: G. Loi
Author: E. Negri
Author: M. Brambilla
Author: N. Chiodini
Author: G. Brambilla ORCID iD
Author: A. Vedda

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