Johnston, DA (2006) Genomes and genomics of parasitic flatworms. In, Maule, AG and Marks, NJ (eds.) Parasitic Flatworms: : Molecular biology, biochemistry, immunology and physiology. Wallingford, UK. Centre for Agriculture and Biosciences International, pp. 37-80. (doi:10.1079/9780851990279.0037).
Abstract
This chapter describes the genome (genome size, genome composition DNA methylation, repeat sequences, integration of host DNA sequences, genome instability, gene processing), karyotype (chromosome number, ploidy, sex chromosomes, recombination frequency and telomeres), and mitochondrial genome (gene order, genetic code, maternal inheritance) features of parasitic flatworms. The methods used in the analysis of flatworm genomes (gene discovery and transcriptome analysis, physical mapping, chromosome mapping, genome sequencing) are also discussed.
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