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Risk of Long Covid in people infected with SARS-CoV-2 after two doses of a COVID-19 vaccine: community-based, matched cohort study

Risk of Long Covid in people infected with SARS-CoV-2 after two doses of a COVID-19 vaccine: community-based, matched cohort study
Risk of Long Covid in people infected with SARS-CoV-2 after two doses of a COVID-19 vaccine: community-based, matched cohort study
We investigated Long Covid incidence by vaccination status in a random sample of UK adults from April 2020 to November 2021. Persistent symptoms were reported by 9.5% of 3,090 breakthrough SARS-CoV-2 infections and 14.6% of unvaccinated controls (adjusted odds ratio 0.59, 95% CI: 0.50-0.69), emphasising the need for public health initiatives to increase population-level vaccine uptake.
COVID-19, Long Covid, Vaccination, Coronavirus, Post-COVID Condition
2328-8957
Ayoubkhani, Daniel
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Bosworth, Matthew L.
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King, Sasha
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Pouwels, Koen B.
13716648-03db-4375-b5d6-ec4af79f23a0
Glickman, Myer
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Nafilyan, Vahé
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Zaccardi, Francesco
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Khunti, Kamlesh
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Alwan, Nisreen
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Walker, Ann Sarah
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Ayoubkhani, Daniel
cfd1b0e2-6685-4edb-a53f-299582b89280
Bosworth, Matthew L.
05d73c95-7103-4d63-9764-c2dba76f0c22
King, Sasha
a7550d5a-f11d-4457-a9a8-0cdd70ebe49c
Pouwels, Koen B.
13716648-03db-4375-b5d6-ec4af79f23a0
Glickman, Myer
61b66cbc-a403-4cd6-b7b5-eb18fccae968
Nafilyan, Vahé
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Zaccardi, Francesco
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Khunti, Kamlesh
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Alwan, Nisreen
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Walker, Ann Sarah
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Ayoubkhani, Daniel, Bosworth, Matthew L., King, Sasha, Pouwels, Koen B., Glickman, Myer, Nafilyan, Vahé, Zaccardi, Francesco, Khunti, Kamlesh, Alwan, Nisreen and Walker, Ann Sarah (2022) Risk of Long Covid in people infected with SARS-CoV-2 after two doses of a COVID-19 vaccine: community-based, matched cohort study. Open Forum Infectious Diseases, 9 (9), [ofac464]. (doi:10.1093/ofid/ofac464).

Record type: Article

Abstract

We investigated Long Covid incidence by vaccination status in a random sample of UK adults from April 2020 to November 2021. Persistent symptoms were reported by 9.5% of 3,090 breakthrough SARS-CoV-2 infections and 14.6% of unvaccinated controls (adjusted odds ratio 0.59, 95% CI: 0.50-0.69), emphasising the need for public health initiatives to increase population-level vaccine uptake.

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More information

Accepted/In Press date: 6 September 2022
e-pub ahead of print date: 12 September 2022
Keywords: COVID-19, Long Covid, Vaccination, Coronavirus, Post-COVID Condition

Identifiers

Local EPrints ID: 469590
URI: http://eprints.soton.ac.uk/id/eprint/469590
ISSN: 2328-8957
PURE UUID: 1bb4bdf9-4e59-4fde-b096-9c4806484f35
ORCID for Nisreen Alwan: ORCID iD orcid.org/0000-0002-4134-8463

Catalogue record

Date deposited: 20 Sep 2022 17:11
Last modified: 01 Feb 2023 17:31

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Contributors

Author: Daniel Ayoubkhani
Author: Matthew L. Bosworth
Author: Sasha King
Author: Koen B. Pouwels
Author: Myer Glickman
Author: Vahé Nafilyan
Author: Francesco Zaccardi
Author: Kamlesh Khunti
Author: Nisreen Alwan ORCID iD
Author: Ann Sarah Walker

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