The University of Southampton
×
Filter your search:
University of Southampton Institutional Repository

A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide

A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide
A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide

Since the beginning of the COVID-19 pandemic, there has been an increased need for the development of novel diagnostic solutions that can accurately and rapidly detect SARS-CoV-2 infection. In this work, we demonstrate the targeting of viral oligonucleotide markers within minutes without the requirement of a polymerase chain reaction (PCR) amplification step via the use of oligonucleotide-coated upconversion nanoparticles (UCNPs) and graphene oxide (GO).

2046-2069
18445-18449
Alexaki, Konstantina
4eb3b612-8a61-41cc-855e-7ccf917310f7
Kyriazi, Maria Eleni
3cfe9662-4e7f-49bc-b707-ccc2b4da6b09
Greening, Joshua
e74bf8ad-15c9-49cd-848d-d7e392435c4e
Taemaitree, Lapatrada
c069b3ef-6d34-4a85-a351-2576fb01af64
El-Sagheer, Afaf H.
05b8295a-64ad-4fdf-ad57-c34934a46c04
Brown, Tom
a64aae36-bb30-42df-88a2-11be394e8c89
Zhang, Xunli
d7cf1181-3276-4da1-9150-e212b333abb1
Muskens, Otto L.
2284101a-f9ef-4d79-8951-a6cda5bfc7f9
Kanaras, Antonios G.
667ecfdc-7647-4bd8-be03-a47bf32504c7
Alexaki, Konstantina
4eb3b612-8a61-41cc-855e-7ccf917310f7
Kyriazi, Maria Eleni
3cfe9662-4e7f-49bc-b707-ccc2b4da6b09
Greening, Joshua
e74bf8ad-15c9-49cd-848d-d7e392435c4e
Taemaitree, Lapatrada
c069b3ef-6d34-4a85-a351-2576fb01af64
El-Sagheer, Afaf H.
05b8295a-64ad-4fdf-ad57-c34934a46c04
Brown, Tom
a64aae36-bb30-42df-88a2-11be394e8c89
Zhang, Xunli
d7cf1181-3276-4da1-9150-e212b333abb1
Muskens, Otto L.
2284101a-f9ef-4d79-8951-a6cda5bfc7f9
Kanaras, Antonios G.
667ecfdc-7647-4bd8-be03-a47bf32504c7

Alexaki, Konstantina, Kyriazi, Maria Eleni, Greening, Joshua, Taemaitree, Lapatrada, El-Sagheer, Afaf H., Brown, Tom, Zhang, Xunli, Muskens, Otto L. and Kanaras, Antonios G. (2022) A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide. RSC Advances, 12 (29), 18445-18449. (doi:10.1039/d2ra03599e).

Record type: Article

Abstract

Since the beginning of the COVID-19 pandemic, there has been an increased need for the development of novel diagnostic solutions that can accurately and rapidly detect SARS-CoV-2 infection. In this work, we demonstrate the targeting of viral oligonucleotide markers within minutes without the requirement of a polymerase chain reaction (PCR) amplification step via the use of oligonucleotide-coated upconversion nanoparticles (UCNPs) and graphene oxide (GO).

Text
d2ra03599e - Version of Record
Available under License Creative Commons Attribution.
Download (620kB)

More information

Accepted/In Press date: 22 June 2022
Published date: 22 June 2022
Additional Information: Funding Information: A. G. K. and J. G. would like to thank the University of Southampton for a DTP PhD Scholarship. K. A. would like to thank the School of Physics and Astronomy for a Mayflower studentship. A. G. K. and M. E. K. would like to thank funding from BBSRC (Grant No. BB/N021150/1).
Learn more about Institute for Life Sciences research Learn more about School of Physics and Astronomy research

Identifiers

Local EPrints ID: 469901
URI: http://eprints.soton.ac.uk/id/eprint/469901
DOI: doi:10.1039/d2ra03599e
ISSN: 2046-2069
PURE UUID: a8fffb52-b457-4619-b08d-6bdd782fce16
ORCID for Konstantina Alexaki: ORCID iD orcid.org/0000-0002-8702-2696
ORCID for Afaf H. El-Sagheer: ORCID iD orcid.org/0000-0001-8706-1292
ORCID for Xunli Zhang: ORCID iD orcid.org/0000-0002-4375-1571
ORCID for Otto L. Muskens: ORCID iD orcid.org/0000-0003-0693-5504
ORCID for Antonios G. Kanaras: ORCID iD orcid.org/0000-0002-9847-6706

Catalogue record

Date deposited: 28 Sep 2022 16:43
Last modified: 17 Mar 2024 03:18

Export record

Altmetrics

Contributors

Author: Konstantina Alexaki ORCID iD
Author: Maria Eleni Kyriazi
Author: Joshua Greening
Author: Lapatrada Taemaitree
Author: Afaf H. El-Sagheer ORCID iD
Author: Tom Brown
Author: Xunli Zhang ORCID iD
Author: Otto L. Muskens ORCID iD
Author: Antonios G. Kanaras ORCID iD

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Library staff additional information
Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×