A randomised controlled trial of EndoRings assisted colonoscopy versus standard colonoscopy
A randomised controlled trial of EndoRings assisted colonoscopy versus standard colonoscopy
Endorings is a distal attachment consisting of two layers of circular flexible rings that evert mucosal folds.
Aims: Investigate if Endorings Colonoscopy (ER) improves polyp and adenoma detection compared to standard colonoscopy (SC).
Methods: Multi-centre, parallel group, randomised controlled trial.
Results: Total of 556 patients randomised to ER (275) or SC (281). Colonoscopy completed 532/556 (96%) cases. EndoRings removed in 74/275 (27%) patients. Total number of polyps in ER limb 582 vs 515 in SC limb, p=0.04. Total number of adenomas in ER limb 361 vs 343 for SC limb, p=0.49. A statistically significant difference in the mean number of polyps per patient in both the Intention to Treat (ITT) (1.84 SC vs 2.10 ER, p-value 0.027) and Per Protocol (PP) (1.84 SC vs 2.25 ER, p-value 0.004).
Conclusions: Our study shows promise for the EndoRings device to improve polyp detection.
354-360
Thayalasekaran, Sreedhari
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Bhattacharyya, Rupam
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Chedgy, Fergus
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Basford, Peter
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Subramaniam, Sharmila
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Kandiah, Kesavan
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Thursby-Pelham, Fergus
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Brown, James
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Alkandari, Asma
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Ellis, Richard
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Coda, Sergio
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Goggin, Patrick
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Amos, Mark
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Fogg, Carole
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Longcroft-Wheaton, Gaius
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Bhandari, Pradeep
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9 September 2022
Thayalasekaran, Sreedhari
faeaf07c-7303-46ae-a400-c06754712695
Bhattacharyya, Rupam
eca7ab48-ad03-47b7-9b32-e8d71031d7b2
Chedgy, Fergus
143cea93-6dbc-474c-ba84-d70b7396993a
Basford, Peter
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Subramaniam, Sharmila
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Kandiah, Kesavan
65a0a577-cb0b-4b9c-b1b5-d44d4a266285
Thursby-Pelham, Fergus
664ff399-6985-494d-8350-fa87278b642a
Brown, James
dec266a5-ae8d-4351-963f-553c8d1b7b0c
Alkandari, Asma
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Ellis, Richard
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Coda, Sergio
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Goggin, Patrick
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Amos, Mark
849d8356-a09d-4b54-8df7-8839081d59ce
Fogg, Carole
42057537-d443-462a-8944-c804252c973b
Longcroft-Wheaton, Gaius
c81264ad-35a8-4601-a001-d7cfb6357863
Bhandari, Pradeep
1128a294-31d8-4871-a49e-781284b7ecdf
Thayalasekaran, Sreedhari, Bhattacharyya, Rupam, Chedgy, Fergus, Basford, Peter, Subramaniam, Sharmila, Kandiah, Kesavan, Thursby-Pelham, Fergus, Brown, James, Alkandari, Asma, Ellis, Richard, Coda, Sergio, Goggin, Patrick, Amos, Mark, Fogg, Carole, Longcroft-Wheaton, Gaius and Bhandari, Pradeep
(2022)
A randomised controlled trial of EndoRings assisted colonoscopy versus standard colonoscopy.
Digestive Endoscopy, 35, .
Abstract
Endorings is a distal attachment consisting of two layers of circular flexible rings that evert mucosal folds.
Aims: Investigate if Endorings Colonoscopy (ER) improves polyp and adenoma detection compared to standard colonoscopy (SC).
Methods: Multi-centre, parallel group, randomised controlled trial.
Results: Total of 556 patients randomised to ER (275) or SC (281). Colonoscopy completed 532/556 (96%) cases. EndoRings removed in 74/275 (27%) patients. Total number of polyps in ER limb 582 vs 515 in SC limb, p=0.04. Total number of adenomas in ER limb 361 vs 343 for SC limb, p=0.49. A statistically significant difference in the mean number of polyps per patient in both the Intention to Treat (ITT) (1.84 SC vs 2.10 ER, p-value 0.027) and Per Protocol (PP) (1.84 SC vs 2.25 ER, p-value 0.004).
Conclusions: Our study shows promise for the EndoRings device to improve polyp detection.
Text
Digestive Endoscopy - 2022 - Thayalasekaran - A Randomised Controlled Trial of EndoRingsTM Assisted Colonoscopy Versus (1)
- Accepted Manuscript
More information
Accepted/In Press date: 6 September 2022
e-pub ahead of print date: 9 September 2022
Published date: 9 September 2022
Identifiers
Local EPrints ID: 469978
URI: http://eprints.soton.ac.uk/id/eprint/469978
PURE UUID: a148a179-0808-4420-85b0-a563d18a11bb
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Date deposited: 29 Sep 2022 16:45
Last modified: 17 Mar 2024 07:30
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Contributors
Author:
Sreedhari Thayalasekaran
Author:
Rupam Bhattacharyya
Author:
Fergus Chedgy
Author:
Peter Basford
Author:
Sharmila Subramaniam
Author:
Kesavan Kandiah
Author:
Fergus Thursby-Pelham
Author:
James Brown
Author:
Asma Alkandari
Author:
Richard Ellis
Author:
Sergio Coda
Author:
Patrick Goggin
Author:
Mark Amos
Author:
Gaius Longcroft-Wheaton
Author:
Pradeep Bhandari
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