Blistering eruption on an elderly woman's leg - Quiz case
Blistering eruption on an elderly woman's leg - Quiz case
The skin biopsy specimen showed an extremely dense and extensive inflammatory infiltrate occupying all of the dermis except for the papillary dermis, which was grossly edematous. The overlying epidermis contained a scattering of lymphocytes and foci of spongiosis with cell degeneration. The dermal infiltrate consisted of a dense mass of neutrophils, most of which appeared to have a normal morphological appearance. Hemorrhage and edema were also present, and in the relatively spared areas, small blood vessels showed very marked endothelial swelling. A definite leukemic infiltrate was not identified. The microscopic features were in keeping with a primary neutrophilic dermatosis, such as PG or Sweet syndrome. The features seemed most consistent with PG
479-484
Ardern-Jones, Michael R.
7ac43c24-94ab-4d19-ba69-afaa546bec90
James, Martin P.
41ffefa0-ce84-4688-ac7a-56bec8f16fab
1 April 2004
Ardern-Jones, Michael R.
7ac43c24-94ab-4d19-ba69-afaa546bec90
James, Martin P.
41ffefa0-ce84-4688-ac7a-56bec8f16fab
Ardern-Jones, Michael R. and James, Martin P.
(2004)
Blistering eruption on an elderly woman's leg - Quiz case.
Archives of Dermatology, 140 (4), .
(doi:10.1001/archderm.140.4.479-g).
Abstract
The skin biopsy specimen showed an extremely dense and extensive inflammatory infiltrate occupying all of the dermis except for the papillary dermis, which was grossly edematous. The overlying epidermis contained a scattering of lymphocytes and foci of spongiosis with cell degeneration. The dermal infiltrate consisted of a dense mass of neutrophils, most of which appeared to have a normal morphological appearance. Hemorrhage and edema were also present, and in the relatively spared areas, small blood vessels showed very marked endothelial swelling. A definite leukemic infiltrate was not identified. The microscopic features were in keeping with a primary neutrophilic dermatosis, such as PG or Sweet syndrome. The features seemed most consistent with PG
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Published date: 1 April 2004
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Local EPrints ID: 470083
URI: http://eprints.soton.ac.uk/id/eprint/470083
ISSN: 2168-6068
PURE UUID: fdf1ae71-53b9-4008-8dc0-c3fd3a8696d4
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Date deposited: 03 Oct 2022 16:39
Last modified: 17 Mar 2024 03:10
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Author:
Martin P. James
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