Linkage map integration
Linkage map integration
The algorithms that drive the map+ program for locus-oriented linkage mapping are presented. They depend on the enhanced location database program ldb+ to specify an initial comprehensive map that includes all loci in the summary lod file. Subsequently the map may be edited or order constrained and is automatically improved by estimating the location of each locus conditional on the remainder, beginning with the most discrepant loci. Operating characteristics permit rapid and accurate construction of linkage maps with several hundred loci. The map+ program also performs nondisjunction mapping with tests of nonstandard recombination. We have released map+ on Internet as a source program in the C language together with the location database that now includes the LODSOURCE database. The anonymous ftp is cedar.genetics.soton.ac.uk and the World Wide Web address is http://cedar.genetics.soton.ac.uk/public html. (C) 1996 Academic Press, Inc.
157-162
Collins, A.
7daa83eb-0b21-43b2-af1a-e38fb36e2a64
Teague, J. W.
481bf04e-9cd4-4acf-8824-2a5f7cfc9dca
Keats, B. J.
1e85e190-0afd-4831-88e0-0f4153a0614e
Morton, N. E.
c668e2be-074a-4a0a-a2ca-e8f51830ebb7
15 August 1996
Collins, A.
7daa83eb-0b21-43b2-af1a-e38fb36e2a64
Teague, J. W.
481bf04e-9cd4-4acf-8824-2a5f7cfc9dca
Keats, B. J.
1e85e190-0afd-4831-88e0-0f4153a0614e
Morton, N. E.
c668e2be-074a-4a0a-a2ca-e8f51830ebb7
Collins, A., Teague, J. W., Keats, B. J. and Morton, N. E.
(1996)
Linkage map integration.
Genomics, 36 (1), .
(doi:10.1006/geno.1996.0436).
Abstract
The algorithms that drive the map+ program for locus-oriented linkage mapping are presented. They depend on the enhanced location database program ldb+ to specify an initial comprehensive map that includes all loci in the summary lod file. Subsequently the map may be edited or order constrained and is automatically improved by estimating the location of each locus conditional on the remainder, beginning with the most discrepant loci. Operating characteristics permit rapid and accurate construction of linkage maps with several hundred loci. The map+ program also performs nondisjunction mapping with tests of nonstandard recombination. We have released map+ on Internet as a source program in the C language together with the location database that now includes the LODSOURCE database. The anonymous ftp is cedar.genetics.soton.ac.uk and the World Wide Web address is http://cedar.genetics.soton.ac.uk/public html. (C) 1996 Academic Press, Inc.
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Published date: 15 August 1996
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Local EPrints ID: 470614
URI: http://eprints.soton.ac.uk/id/eprint/470614
ISSN: 0888-7543
PURE UUID: 52081c1d-5f4f-4baf-8ab5-a6ddac527b1d
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Date deposited: 14 Oct 2022 16:44
Last modified: 17 Mar 2024 02:37
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Author:
J. W. Teague
Author:
B. J. Keats
Author:
N. E. Morton
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