Likelihood ratios for DNA identification
Likelihood ratios for DNA identification
Likelihood ratio (LR) tests are provided for the three alternatives to DNA identity: exclusion, coincidence, and kinship. The coincidence test uses the radius of coalescence to conserve the observed frequency of single band phenotypes. Genotype probabilities under kinship are derived for mating groups, specified relatives, and structured populations; and unbiased estimates of the genetic parameters are provided. The LR is made robust to gene frequency errors by specifying the mean matching probability, and the tolerable loss of information this entails is determined by LR theory. This straightforward application of the seminal work of Jerzy Neyman and Sewall Wright strongly supports the use of LRs and kinship for presentation of DNA evidence by expert witnesses and committees.
DNA typing, forensic science, population structure
6007-6011
Collins, A.
7daa83eb-0b21-43b2-af1a-e38fb36e2a64
Morton, N. E.
c668e2be-074a-4a0a-a2ca-e8f51830ebb7
21 June 1994
Collins, A.
7daa83eb-0b21-43b2-af1a-e38fb36e2a64
Morton, N. E.
c668e2be-074a-4a0a-a2ca-e8f51830ebb7
Collins, A. and Morton, N. E.
(1994)
Likelihood ratios for DNA identification.
Proceedings of the National Academy of Sciences, 91 (13), .
(doi:10.1073/pnas.91.13.6007).
Abstract
Likelihood ratio (LR) tests are provided for the three alternatives to DNA identity: exclusion, coincidence, and kinship. The coincidence test uses the radius of coalescence to conserve the observed frequency of single band phenotypes. Genotype probabilities under kinship are derived for mating groups, specified relatives, and structured populations; and unbiased estimates of the genetic parameters are provided. The LR is made robust to gene frequency errors by specifying the mean matching probability, and the tolerable loss of information this entails is determined by LR theory. This straightforward application of the seminal work of Jerzy Neyman and Sewall Wright strongly supports the use of LRs and kinship for presentation of DNA evidence by expert witnesses and committees.
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Published date: 21 June 1994
Keywords:
DNA typing, forensic science, population structure
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Local EPrints ID: 470937
URI: http://eprints.soton.ac.uk/id/eprint/470937
ISSN: 0027-8424
PURE UUID: 708042d1-d3b1-47d4-93bf-27ea5099c1e7
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Date deposited: 21 Oct 2022 16:34
Last modified: 17 Mar 2024 02:38
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Author:
N. E. Morton
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