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Is the UK prepared for seasonal influenza in 2022–23 and beyond?

Is the UK prepared for seasonal influenza in 2022–23 and beyond?
Is the UK prepared for seasonal influenza in 2022–23 and beyond?
Non-pharmaceutical interventions for COVID-19 have resulted in very low levels of circulating influenza globally. However, now that these pandemic control measures have been abandoned in the UK, the return of influenza as a major public health issue appears inevitable. There has been a rapid rise in influenza A notifications in Australia, which started earlier than usual and as of writing are tracking at record high numbers (figure). These data from Australia help predict what is to come in the northern hemisphere in the winter of 2022–23. As of June 19, 2022, 85% of influenza cases in Australia were due to influenza A (H3N2), 1 which is known to cause more severe epidemics. 2 The sharp increase in cases was probably driven by relaxation of measures put in place to mitigate the COVID-19 pandemic and the low proportion of the population vaccinated against influenza. In addition, there has been little natural …
1473-3099
1280 - 1281
Clark, Tristan
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Nazareth, Joshua
f40b13c7-8f7c-440b-ba54-824410bffe2e
Pan, Daniel
40159bcd-4a92-4504-8a99-cc10ff084b1c
Martin, Christopher
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Burr, Ian
d7030919-ebfd-4e2b-9c80-6cb063b81261
Sullivan, Sheena
6b17c8e9-da04-4072-92a2-b597d838105e
Stephenson, Iain
3608f665-82f8-4372-8051-e70361b63cb8
Nellums, Laura
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Sahota, Amandeep
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Tang, Julian
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Pareek, Manish
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Clark, Tristan
712ec18e-613c-45df-a013-c8a22834e14f
Nazareth, Joshua
f40b13c7-8f7c-440b-ba54-824410bffe2e
Pan, Daniel
40159bcd-4a92-4504-8a99-cc10ff084b1c
Martin, Christopher
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Burr, Ian
d7030919-ebfd-4e2b-9c80-6cb063b81261
Sullivan, Sheena
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Stephenson, Iain
3608f665-82f8-4372-8051-e70361b63cb8
Nellums, Laura
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Sahota, Amandeep
8003228e-ca6f-47c1-8704-9e9cda9d7655
Tang, Julian
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Pareek, Manish
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Clark, Tristan, Nazareth, Joshua, Pan, Daniel, Martin, Christopher, Burr, Ian, Sullivan, Sheena, Stephenson, Iain, Nellums, Laura, Sahota, Amandeep, Tang, Julian and Pareek, Manish (2022) Is the UK prepared for seasonal influenza in 2022–23 and beyond? The Lancet Infectious Diseases, 22 (9), 1280 - 1281. (doi:10.1016/S1473-3099(22)00503-5).

Record type: Letter

Abstract

Non-pharmaceutical interventions for COVID-19 have resulted in very low levels of circulating influenza globally. However, now that these pandemic control measures have been abandoned in the UK, the return of influenza as a major public health issue appears inevitable. There has been a rapid rise in influenza A notifications in Australia, which started earlier than usual and as of writing are tracking at record high numbers (figure). These data from Australia help predict what is to come in the northern hemisphere in the winter of 2022–23. As of June 19, 2022, 85% of influenza cases in Australia were due to influenza A (H3N2), 1 which is known to cause more severe epidemics. 2 The sharp increase in cases was probably driven by relaxation of measures put in place to mitigate the COVID-19 pandemic and the low proportion of the population vaccinated against influenza. In addition, there has been little natural …

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e-pub ahead of print date: 24 August 2022
Published date: September 2022
Additional Information: Funding Information: DP reports a doctoral research fellowship from the National Institute for Health and Care Research. IB reports shares in CSL. SGS reports support from WHO “to conduct a systematic review, appraisal and grading of evidence on repeat seasonal influenza vaccination” and the National Institutes of Health (R01AI141534); OptumLabs research credits through the University of California (no funding received, but access to data granted for 1 year); participation in advisory boards (no remuneration received) for influenza vaccines at Seqiris and Sanofi; serving as an unpaid member of the WHO Strategic Advisory Group of Experts on Immunization Working Group on Influenza from 2017 to 2021; being, since 2011, an observer or invited member of the National Influenza Surveillance Committee (unpaid); and funding to her employer, the WHO Collaborating Centre for Reference and Research on Influenza, for the development of influenza vaccines from Sanofi and International Federation of Pharmaceutical Manufacturers and Associations. TWC reports consulting fees from Biofire/BioMerieux, QIAGEN, Cepheid, Sanofi, and Roche/Shionogi; payment from QIAGEN, Biofire/BioMerieux, and Janssen for a diagnostics educational event and presentations at conferences; participating on a data and safety monitoring board for Roche/Shionogi for an influenza antiviral trial; and receiving equipment from Biofire/BioMerieux and QIAGEN for independent trials of respiratory virus diagnostics. JWT and MP report an investigator-led grant paid to their institution from Sanofi, outside the submitted work. MP reports grants paid to their institution, from Gilead Sciences and consulting fees from QIAGEN, outside the submitted work. All other authors declare no competing interests.

Identifiers

Local EPrints ID: 471400
URI: http://eprints.soton.ac.uk/id/eprint/471400
ISSN: 1473-3099
PURE UUID: cc4f9406-7190-4597-92ac-bb6d765c45bf
ORCID for Tristan Clark: ORCID iD orcid.org/0000-0001-6026-5295

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Date deposited: 07 Nov 2022 17:31
Last modified: 08 Nov 2022 02:43

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Contributors

Author: Tristan Clark ORCID iD
Author: Joshua Nazareth
Author: Daniel Pan
Author: Christopher Martin
Author: Ian Burr
Author: Sheena Sullivan
Author: Iain Stephenson
Author: Laura Nellums
Author: Amandeep Sahota
Author: Julian Tang
Author: Manish Pareek

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