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Nematode pharmacology: neurotransmitters, receptors, and experimental approaches

Nematode pharmacology: neurotransmitters, receptors, and experimental approaches
Nematode pharmacology: neurotransmitters, receptors, and experimental approaches
This chapter focuses on the advantages and limitations of nematodes as pharmacological models, neurotransmitter receptor systems and intracellular signaling cascades and Caenorhabditis elegans and drug discovery. The efficacy of some experimental approaches developed to understand the effects of drugs and chemicals that are used to treat parasitic nematode infections of animals and plants is also discussed.
127-164
CABI
Walker, Robert J.
9368ac2d-f1e9-4bd9-a4b4-4a161c4aa140
Holden-dye, Lindy
8032bf60-5db6-40cb-b71c-ddda9d212c8e
O’connor, Vincent
3c336b62-f3ef-4f78-a44c-ddc7b47bac3f
Dillon, James
f406e30a-3ad4-4a53-80db-6694bab5e3ed
Dudkiewicz, Katarzyna
e7b14c3c-fefa-4a76-afda-b803187a6b4a
Calahorro, Fernando
81b5dd15-c2cc-4470-98d3-9952aca6fb64
Glazer, Itamar
Shapiro-llan, D
Sternberg, Paul W.
Walker, Robert J.
9368ac2d-f1e9-4bd9-a4b4-4a161c4aa140
Holden-dye, Lindy
8032bf60-5db6-40cb-b71c-ddda9d212c8e
O’connor, Vincent
3c336b62-f3ef-4f78-a44c-ddc7b47bac3f
Dillon, James
f406e30a-3ad4-4a53-80db-6694bab5e3ed
Dudkiewicz, Katarzyna
e7b14c3c-fefa-4a76-afda-b803187a6b4a
Calahorro, Fernando
81b5dd15-c2cc-4470-98d3-9952aca6fb64
Glazer, Itamar
Shapiro-llan, D
Sternberg, Paul W.

Walker, Robert J., Holden-dye, Lindy, O’connor, Vincent, Dillon, James, Dudkiewicz, Katarzyna and Calahorro, Fernando (2022) Nematode pharmacology: neurotransmitters, receptors, and experimental approaches. In, Glazer, Itamar, Shapiro-llan, D and Sternberg, Paul W. (eds.) Nematodes as Model Organisms. CABI, pp. 127-164. (doi:10.1079/9781789248814.0006).

Record type: Book Section

Abstract

This chapter focuses on the advantages and limitations of nematodes as pharmacological models, neurotransmitter receptor systems and intracellular signaling cascades and Caenorhabditis elegans and drug discovery. The efficacy of some experimental approaches developed to understand the effects of drugs and chemicals that are used to treat parasitic nematode infections of animals and plants is also discussed.

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e-pub ahead of print date: 12 July 2022

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Local EPrints ID: 471401
URI: http://eprints.soton.ac.uk/id/eprint/471401
PURE UUID: 817dd05d-dae8-4254-8bdb-2d7b4bc5b3e5
ORCID for Robert J. Walker: ORCID iD orcid.org/0000-0002-9031-7671
ORCID for Lindy Holden-dye: ORCID iD orcid.org/0000-0002-9704-1217
ORCID for James Dillon: ORCID iD orcid.org/0000-0003-3244-7483

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Date deposited: 07 Nov 2022 17:31
Last modified: 08 Nov 2022 02:53

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Contributors

Author: Vincent O’connor
Author: James Dillon ORCID iD
Author: Katarzyna Dudkiewicz
Author: Fernando Calahorro
Editor: Itamar Glazer
Editor: D Shapiro-llan
Editor: Paul W. Sternberg

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