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Type 1 diabetes incidence and prevalence trends in a cohort of Canadian children and youth

Type 1 diabetes incidence and prevalence trends in a cohort of Canadian children and youth
Type 1 diabetes incidence and prevalence trends in a cohort of Canadian children and youth
Background and Objective: Incidence rates of type 1 diabetes have long been on the rise across the globe, however, there is emerging evidence that the rate of rise may be slowing. The objective of this study was to describe trends in the incidence and prevalence of type 1 diabetes in a sample of Canadian children and youth. Methods: Cases were extracted using linked administrative datasets and a validated diabetes case-finding definition. Incidence and prevalence trends were analyzed using the JoinPoint regression analysis program.
Results: A small increase in the incidence of type 1 diabetes was observed over the 11-year period from 2002-2003 to 2012-2013. Total incident cases per year ranged from 201 (2005-2006) to 250 (2007-2008). Total prevalent cases per year ranged from 1790 (2002-2003) to 2264 (2012-2013). Incidence was highest among children aged 5 to 14?years, and lowest in the youngest (1-4?years) and oldest (15-19?years) age brackets. The most significant increase in incidence was in children aged 10 to 14?years. Age-standardized prevalence increased significantly throughout the study period.
Conclusion:These results are similar to data from the United States but differ from European data with respect to the annual percent change for incidence as well as age-specific incidence trends. In keeping with the low mortality rates associated with type 1 diabetes, the prevalence continues to rise.
epidemiology, pediatrics, trends, type 1 diabetes
1399-543X
501-505
Fox, Danya A.
8aa6a667-88de-4ca4-81f2-2ce339199980
Islam, Nazrul
e5345196-7479-438f-b4f6-c372d2135586
Sutherland, Jenny
10e04850-1729-4969-9035-43588daf0ad1
Reimer, Kim
6bcb6ea2-9b4b-4b1b-afb4-686f98be5aac
Amed, Shazhan
c3afda99-2743-404a-ba72-38eb0fcc69dc
Fox, Danya A.
8aa6a667-88de-4ca4-81f2-2ce339199980
Islam, Nazrul
e5345196-7479-438f-b4f6-c372d2135586
Sutherland, Jenny
10e04850-1729-4969-9035-43588daf0ad1
Reimer, Kim
6bcb6ea2-9b4b-4b1b-afb4-686f98be5aac
Amed, Shazhan
c3afda99-2743-404a-ba72-38eb0fcc69dc

Fox, Danya A., Islam, Nazrul, Sutherland, Jenny, Reimer, Kim and Amed, Shazhan (2018) Type 1 diabetes incidence and prevalence trends in a cohort of Canadian children and youth. Pediatric Diabetes, 19 (3), 501-505. (doi:10.1111/pedi.12566).

Record type: Article

Abstract

Background and Objective: Incidence rates of type 1 diabetes have long been on the rise across the globe, however, there is emerging evidence that the rate of rise may be slowing. The objective of this study was to describe trends in the incidence and prevalence of type 1 diabetes in a sample of Canadian children and youth. Methods: Cases were extracted using linked administrative datasets and a validated diabetes case-finding definition. Incidence and prevalence trends were analyzed using the JoinPoint regression analysis program.
Results: A small increase in the incidence of type 1 diabetes was observed over the 11-year period from 2002-2003 to 2012-2013. Total incident cases per year ranged from 201 (2005-2006) to 250 (2007-2008). Total prevalent cases per year ranged from 1790 (2002-2003) to 2264 (2012-2013). Incidence was highest among children aged 5 to 14?years, and lowest in the youngest (1-4?years) and oldest (15-19?years) age brackets. The most significant increase in incidence was in children aged 10 to 14?years. Age-standardized prevalence increased significantly throughout the study period.
Conclusion:These results are similar to data from the United States but differ from European data with respect to the annual percent change for incidence as well as age-specific incidence trends. In keeping with the low mortality rates associated with type 1 diabetes, the prevalence continues to rise.

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More information

Published date: 1 May 2018
Keywords: epidemiology, pediatrics, trends, type 1 diabetes

Identifiers

Local EPrints ID: 471611
URI: http://eprints.soton.ac.uk/id/eprint/471611
ISSN: 1399-543X
PURE UUID: 0da6e2bd-fd59-4228-8982-328e697c0c3a
ORCID for Nazrul Islam: ORCID iD orcid.org/0000-0003-3982-4325

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Date deposited: 14 Nov 2022 18:12
Last modified: 17 Mar 2024 04:15

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Contributors

Author: Danya A. Fox
Author: Nazrul Islam ORCID iD
Author: Jenny Sutherland
Author: Kim Reimer
Author: Shazhan Amed

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